Design, synthesis, and applications of stereospecific 1,3-diene carbonyls

被引：0

作者：

Qiang Feng ^{[1
]}

Shihui Wang ^{[1
]}

Xingxing Ma ^{[2
]}

Changqing Rao ^{[1
]}

Qiuling Song ^{[1
,2
,3
]}

机构：

[1] Institute of Next Generation Matter Transformation, College of Material Sciences & Engineering, Huaqiao University

[2] Key Laboratory of Molecule Synthesis and Function Discovery, Fujian Province University, College of Chemistry, Fuzhou University

[3] School of Chemistry and Chemical Engineering, Henan Normal University

来源：

Science China(Chemistry) | 2022年 / 65卷 / 05期

关键词：

D O I：

暂无

中图分类号：

O621.3 [有机合成化学];

学科分类号：

070303 ; 081704 ;

摘要：

The strategy toward the synthesis of various 1,3-dienals or 1,3-dienones is disclosed between diazo compounds and furans,which features metal-free, additive-free, broad functional group tolerance, and readily accessible starting materials. Notably, this strategy is applicable in both intramolecular and intermolecular protocols. Mechanistic studies suggested that the reactions undergo a cyclopropanation/rearrangement sequence. With an E/E-1,3-dienal, corresponding N-tosylhydrazones were readily prepared and subjected to phenylboronic acid to form a double bond migration product and indoles to construct a five-member ring via [3 + 2] annulation reaction.

引用

页码：912 / 917

页数：6

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