Novel Non-Protein Biomarkers for Early Detection of Hepatocellular Carcinoma

被引：0

作者：

Ghassan K.Abou-Alfa ^{[1
,2
]}

Lin Wu ^{[3
]}

Augusto Villanueva ^{[4
]}

机构：

[1] Memorial Sloan Kettering Cancer Center, New York City

[2] Weill Medical College, Cornell University, New York City

[3] Berry Oncology Corporation

[4] Division of Liver Diseases, Division of Hematology/Medical Oncology, Liver Cancer Program, Department of Medicine, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai,New York City

来源：

Engineering | 2021年 / 7卷 / 10期

关键词：

D O I：

暂无

中图分类号：

R735.7 [肝肿瘤];

学科分类号：

摘要：

Early detection of hepatocellular carcinoma(HCC) while in its early stages is critical for reducing HCC mortality in high-risk patients.However,highly sensitive and specific surveillance biomarkers for early-stage HCC detection are still lacking.In recent years,great efforts have been made to research tumor-derived molecular features that are detectable in circulation,such as circulating tumor deoxyribonucleic acid and circulating tumor ribonucleic acid,in order to explore their potential as noninvasive biomarker candidates in many tumor types.In this review,we summarize current studies on these new approaches and their application in early HCC detection.

引用

页码：1369 / 1374

页数：6

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