Salivary Gland Branching Morphogenesis——Recent Progress and Future Opportunities

被引：0

作者：

Jeff Chi-feng Hsu

Kenneth M.Yamada

机构：

[1] LaboratoryofCellandDevelopmentalBiology,NationalInstituteofDentalandCraniofacialResearch,NationalInstitutesofHealth

来源：

International Journal of Oral Science | 2010年 / 03期

关键词：

salivary gland; epithelium; branching morpho-genesis; fibronectin; E-cadherin; growth factor;

D O I：

暂无

中图分类号：

R780.2 [口腔病理学];

学科分类号：

100301 ;

摘要：

Salivary glands provide saliva to maintain oral health,and a loss of salivary gland function substantially decreases quality-of-life.Understanding the biological mechanisms that generate salivary glands during embryonic develop-ment may identify novel ways to regenerate function or design artificial salivary glands.This review article summarizes current research on the process of branching morphogenesis of salivary glands,which creates gland structure during development.We highlight exciting new advances and opportunities in studies of cell-cell interactions,mechanical forces,growth factors,and gene expression patterns to improve our understanding of this important process.

引用

页码：117 / 126

页数：10

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