Human papillomavirus-associated diseases and cancers

被引：0

作者：

Lan Yang ^{[1
]}

Jianbo Zhu ^{[1
]}

Xiaoyue Song ^{[1
]}

Yan Qi ^{[1
]}

Xiaobin Cui ^{[1
]}

Feng Li ^{[1
]}

机构：

[1] Department of Pathology and Key Laboratory for Xinjiang Endemic and Ethnic Diseases, Shihezi University School of Medicine

来源：

Oncology and Translational Medicine | 2015年 / 1卷 / 03期

基金：

中国国家自然科学基金;

关键词：

human papillomavirus(HPV); low-risk; high-risk; cancer;

D O I：

暂无

中图分类号：

R511 [病毒传染病]; R730.2 [肿瘤病理学、病因学];

学科分类号：

100214 ; 100401 ;

摘要：

Human papillomaviruses(HPVs) have been detected in cervical cancer cells and skin papilloma cells, which have a variety of types, including low-risk and high-risk types. HPV genome replication requires the host cell’s DNA synthesis machinery, and HPVs encode proteins that maintain differentiated epithelial cells in a replication-competent state. HPV types are tissue-specific and generally produce different types of lesions, either benign or malignant. This review examines different HPV types and their associated diseases and presents therapeutic options for the treatment of HPV-positive diseases.

引用

页码：109 / 114

页数：6

共 29 条

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