Crystal Structure of 3-methyl-1, 2, 3, 4, 4a, 4b, 9a, 15, 15a,15b-decahydro-（4,5）;（4a,15）-dimethano-tricyclo(4, 3, 1, 02,7) deca 〔8, 9, 1, 10-a, b, c〕pyrido〔4,3-a〕-acridin-6-en-9-ol-8-one

被引：0
|
作者：
HU Chun-Hua
CHEN Jian
ZHENG Pei-Ju(Research Center of Analysis and Measurement
QIU Zhui-Bai
YANG Jie(Department of Medicinal Chemistry
机构：
来源：
结构化学 | 1997年 / 03期
关键词：
crystal structure; 6; 14-endo-ethenotetrahydro thebaine;
D O I：
10.14102/j.cnki.0254-5861.1997.03.005
中图分类号：
O76 [晶体结构];
学科分类号：
0702 ; 070205 ; 0703 ; 080501 ;
摘要：
The title compound, C25H24N2O2, a new rearrangement byproduct,has been found in the O-demethylation of 7a-o-amino pheny1-6, 14-endo-ethenotetrahydro thebaine. Its structure was determined by X-ray crystallography. Its crystal isorthorhombic, space group P212121, Mr= 384. 48 with a= 9. 128(2), b= 11. 953 (3),c=17. 422(4) A, V= 1901 (1) A3, Dc= 1. 34 g/cm3, Z= 4, A(MoKa)=0. 71073A,μ= 0. 8 cm-1, F(000) = 816, R= 0. 048, Rw= 0. 051. The molecule is mainly a closedstructure except three extended legs. It consists of a lot of multi-membered rings suchas five- and six- membered rings.
引用
收藏
页码：186 / 190
页数：5
相关论文
共 50 条
  • [1] 1,9a-Epoxy-1,2,3,4,4a,4b,5,8,8a,9a-decahydro-2-methyl-4-nitro-5, 8-methano-9H-fluoren-9-one
    Acta Crystallogr Sect C Cryst Struct Commun, pt 12 (1925-1927):
  • [2] Crystal structure of (4aα,4bα,10aα,10bα)-2,3,4a,10b-tetrachloro-1,4-dioxo-1,4,4a,4b,5,6,7,8,9,10,10a,10b-dodecahydro-benzo[3,4]cyclobuta[1,2]cyclooctane, (C8H14)(C6Cl4O2)
    Peters, K
    Peters, EM
    Braun, M
    Wolff, S
    Christl, M
    ZEITSCHRIFT FUR KRISTALLOGRAPHIE-NEW CRYSTAL STRUCTURES, 2000, 215 (01): : 45 - 46
  • [3] NEUROLEPTICS FROM THE 4A,9B-CIS AND 4A,9B-TRANS-2,3,4,4A,5,9B-HEXAHYDRO-1H-PYRIDO[4,3-B]INDOLE SERIES .2.
    WELCH, WM
    HARBERT, CA
    WEISSMAN, A
    KOE, BK
    JOURNAL OF MEDICINAL CHEMISTRY, 1986, 29 (10) : 2093 - 2099
  • [4] 1,9a-epoxy-1,2,3,4,4a,4b,5,8,8a,9a-decahydro-2-methyl-4-nitro-5,8-methano-9H-fluoren-9-one
    Fun, HK
    Chinnakali, K
    Hazra, NK
    Mal, D
    Nigam, GD
    Razak, IA
    ACTA CRYSTALLOGRAPHICA SECTION C-CRYSTAL STRUCTURE COMMUNICATIONS, 1998, 54 : 1925 - 1927
  • [5] (4'-Acetyloxy-1,3,1'-trioxo-1,3,4,4a,4b,-5,6,7,9,9a-decahydrospiro[indene-2,9'-pyrano[4,3-a]pyrrolizin]-3'-yl)methyl acetate
    Latha, N.
    Rao, J. Naga Siva
    Raghunathan, R.
    Divya, G.
    Lakshmi, S.
    ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2013, 69 : O1764 - +
  • [6] (1S,1 ' S,2 ' R,4a ' S,9a ' S,9b ' R)-1 '-Acetyloxy-2,4 '-dioxo-2 ',4 ',4a ',7 ',8 ',9 ',9a ',9b '-octahydro-1 ' H,2H-spiro[acenaphthylene-1,5 '-pyrano[4,3-a]pyrrolizin]-2 '-yl-methyl acetate
    Santhiya, S.
    Rao, J. Naga Siva
    Raghunatha, R.
    Latha, N.
    Lakshmi, S.
    ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2013, 69 : O1601 - +
  • [7] An unusual impurity 1, 2, 3, 4, 6, 7, 8, 9, 10, 10, 11,11-dodecachloro-1, 4, 4a, 5a, 6, 9, 9a, 9b-octahydro-1, 4, 6, 9-dimethanodibenzofuran formation in minor amount during endosulfan synthesis
    Chakraborty, SK
    Singh, OV
    Sivaramakrishnan, R
    Narasimhan, S
    INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY, 2000, 39 (05): : 399 - 402
  • [8] Crystal structure of methyl 4aR*, 4bR*, 8aS*, 9R*-1-cyano-4b-hydroxy-2,4a,4b,5,6,7,8,8a,9,10-decahydrophenanthrene-9-carboxylate, C17H21NO3
    Dinesh, CU
    Reissig, HU
    Rademacher, O
    ZEITSCHRIFT FUR KRISTALLOGRAPHIE-NEW CRYSTAL STRUCTURES, 2000, 215 (04): : 615 - 616
  • [9] 1,4a,7-Trimethyl-7-vinyl-1,2,3,4,4a,4b,5,6,7,9,10,10a-dodecahydrophenanthrene-1-carboxylic acid
    Chen, Yu-xiang
    Zhao, Zhen-dong
    Gu, Yan
    Wang, Yu-min
    ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2009, 65 : O1117 - U2895
  • [10] cis-[4a]-cisoid-[4a,4b]-cis-[4b]-1,3,6,8,8a,8b-Hexa-methylperhydro-1,3,6,8-tetraazabiphenylene-2,4,5,7-tetraone
    Näther, C
    Krüger, O
    Wille, U
    ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2002, 58 : O409 - O410
12345