Supported by the National Natural Science Foundation of China,a collaborative study by the laboratories of Dr.Song BaoLiang (宋保亮)from Wuhan University and Dr.Ma YiTong (马依彤)from the First Affiliated Hospital of Xinjiang Medical University demonstrates that a rare frameshift mutation in the LIMA1 gene promotes low plasma low-density lipoprotein cholesterol(LDL-C)and decreases intestinal