Experimental study on vasoactive intestinal peptide—like immunoreactivity in plasma and brain in high—velocity missile injuries of extremity

被引:0
作者
李卫平
陈曼娥
刘荫秋
徐有奇
机构
[1] Chongqing 630042
[2] Guangzhou 510515
[3] First Military Medical University
[4] Daping Hosptial
[5] Department of Neurology Nanfang Hospital
[6] Third Military Medical College
关键词
wounds; gunshot; peptides; blood; brain; cerebrospinal fluid; dogs;
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摘要
Experimental high-velocity missile injuries were produced on both hind legs of 15 dogs.It was found that the concentration of vasoactive intestinal peptide-like immunoreactivity(VIP-LI)significantly elevated in both plasma and brain at the early stage after injuries.However,thechanges of VIP-LI concentration in the plasma and brain did not coincide with each other.The re-sults suggest that VIP-LI may participate in the post-traumatic general reaction.The significanceand machanism of the elevation of cerebral VIP-LI level after a severe non-cerebral trauma remainto be clarified.
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页码:36 / 40
页数:5
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