Phosphine-promoted [3+2] cycloaddition between nonsubstituted MBH carbonates and trifluoromethyl ketones

被引：0

作者：

Hong-Yu Duan ^{[1
]}

Juan Ma ^{[1
]}

Zhe-Zhe Yuan ^{[1
]}

Ri-Sheng Yao ^{[1
]}

Wei Tao ^{[1
]}

Fang Xu ^{[1
]}

Hua Xiao ^{[1
,2
]}

Gang Zhao ^{[2
]}

机构：

[1] School of Medical Engineering,Hefei University of Technology

[2] Key Laboratory of Synthetic Chemistry of Natural Substances,Shanghai Institute of Organic Chemistry,Chinese Academy of Sciences

来源：

ChineseChemicalLetters | 2015年 / 26卷 / 06期

基金：

中央高校基本科研业务费专项资金资助; 中国国家自然科学基金;

关键词：

Cycloaddition; Allylic carbonate; Ylides; Trifluoromethyl ketones;

D O I：

暂无

中图分类号：

O621.25 [];

学科分类号：

摘要：

A phosphine-promoted [3 + 2] cycloaddition from readily accessible MBH(Morita–Baylis–Hillman)carbonate and aryl trifluoromethyl ketone is described. The use of methyl vinyl ketone-derived allylic carbonate rather than common acrylate-derived counterpart renders the reaction pathway exclusive for 5-endo process, which enables the expeditious preparation of a range of trifluoromethylated 2,3-dihydrofuran in a chemospecific manner.

引用

页码：646 / 648

页数：3

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