Phosphine-promoted [3+2] cycloaddition between nonsubstituted MBH carbonates and trifluoromethyl ketones

被引：0
|
作者：
Hong-Yu Duan [1 ]
Juan Ma [1 ]
Zhe-Zhe Yuan [1 ]
Ri-Sheng Yao [1 ]
Wei Tao [1 ]
Fang Xu [1 ]
Hua Xiao [1 ,2 ]
Gang Zhao [2 ]
机构：
[1] School of Medical Engineering,Hefei University of Technology
[2] Key Laboratory of Synthetic Chemistry of Natural Substances,Shanghai Institute of Organic Chemistry,Chinese Academy of Sciences
来源：
ChineseChemicalLetters | 2015年 / 26卷 / 06期
基金：
中央高校基本科研业务费专项资金资助; 中国国家自然科学基金;
关键词：
Cycloaddition; Allylic carbonate; Ylides; Trifluoromethyl ketones;
D O I：
暂无
中图分类号：
O621.25 [];
学科分类号：
摘要：
A phosphine-promoted [3 + 2] cycloaddition from readily accessible MBH(Morita–Baylis–Hillman)carbonate and aryl trifluoromethyl ketone is described. The use of methyl vinyl ketone-derived allylic carbonate rather than common acrylate-derived counterpart renders the reaction pathway exclusive for 5-endo process, which enables the expeditious preparation of a range of trifluoromethylated 2,3-dihydrofuran in a chemospecific manner.
引用
收藏
页码：646 / 648
页数：3
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