Current multifunctional albumin-based nanoplatforms for cancer multi-mode therapy

被引：0

作者：

Chang Li ^{[1
]}

Xin Wang ^{[1
]}

Hang Song ^{[2
]}

Shuai Deng ^{[1
]}

Wei Li ^{[3
]}

Jing Li ^{[4
]}

Jin Sun ^{[1
]}

机构：

[1] Wuya College of Innovation,Shenyang Pharmaceutical University

[2] College of Pharmacy,Shenyang Pharmaceutical University

[3] Department of Pharmaceutical Engineering,Shenyang University of Chemical Technology

[4] School of Basic Medical Science,Shenyang Medical College

来源：

Asian Journal of Pharmaceutical Sciences | 2020年 / 15卷 / 01期

关键词：

Albumin; Formulations; Multi-mode therapy; Combination therapy; Stimuli-responsive release;

D O I：

暂无

中图分类号：

R91 [药物基础科学];

学科分类号：

1007 ;

摘要：

Albumin has been widely applied for rational design of drug delivery complexes as natural carriers in cancer therapy due to its distinct advantages of biocompatibility, abundance, low toxicity and versatile property. Hence, various types of multifunctional albumin-based nanoplatforms(MAlb-NPs) that adopt multiple imaging and therapeutic techniques have been developed for cancer diagnosis and treatment. Stimuli-responsive release, including reduction-sensitive, p H-responsive, concentration-dependent and photodynamic-triggered, is important to achieve low-toxicity cancer therapy. Several types of imaging techniques can synergistically improve the effectiveness of cancer therapy. Therefore, combinational theranostic is considered to be a prospective strategy to improve treatment efficiency, minimize side effects and reduce drug resistance, which has received tremendous attentions in recent years. In this review, we highlight several stimuli-responsive albumin nanoplatforms for combinational theranostic.

引用

页码：1 / 12

页数：12

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