THE EFFECT OF ANISODAMINE ON THE MICROVASCULAR PERMEABILITY OF THE LUNGS DURING ARDS

The rats model with ARDS (Adult Respiratory Distress Syndrome)was produced by the way of injecting Eschericbia coli, the effect of anisodamine onthe microvascular permeability of lungs in the rats with ARDS was studied with themethod of Albumin labeled 125I. The experimental results shown that the microvascular permeability of lung in rat with ARDS increased distinctly,but it recovered tothe control arter injecting anisodamine into rat. The function of anisodamine thatrecovered the microvascular Permeability of lungs in rats with ARDS to the controlmay be one of the main principles of anisodamine for curerability of ARDS. It isshown that the anisodamine has profound value for some of diseases with increasingmicrovascular permeability or tissues or organs in clinic.