N-acetyl-L-leucine: a promising treatment option for traumatic brain injury

被引：0
|
作者：
Chinmoy Sarkar [1 ]
Marta M.Lipinski [1 ,2 ]
机构：
[1] Shock,Trauma and Anesthesiology Research (STAR)Center,Department of Anesthesiology,University of Maryland School of Medicine
[2] Department of Anatomy and Neurobiology,University of Maryland School of Medicine
来源：
NeuralRegenerationResearch | 2022年 / 17卷 / 09期
关键词：
D O I：
暂无
中图分类号：
R651.15 [];
学科分类号：
1002 ; 100210 ;
摘要：
Traumatic brain injury (TBI) is a mechanical injury to the brain,which can be sustained due to falls,accidents,contact sports or in combat situation.It is a serious health problem-affecting people of all ages worldwide.As per the recent epidemiological study,more than 55 million people suffer from TBI annually (GBD 2016 Traumatic Brain Injury and Spinal Cord Injury Collaborators,
引用
收藏
页码：1957 / 1958
页数：2
相关论文
共 50 条
  • [1] N-acetyl-L-leucine: a promising treatment option for traumatic brain injury
    Sarkar, Chinmoy
    Lipinski, Marta M.
    NEURAL REGENERATION RESEARCH, 2022, 17 (09) : 1957 - 1958
  • [2] THE PREPARATION OF PURE N-ACETYL-L-LEUCINE AND L-LEUCINE
    DEWITT, HD
    INGERSOLL, AW
    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1951, 73 (07) : 3359 - 3360
  • [3] N-Acetyl-l-leucine improves functional recovery and attenuates cortical cell death and neuroinflammation after traumatic brain injury in mice
    Hegdekar, Nivedita
    Lipinski, Marta M.
    Sarkar, Chinmoy
    SCIENTIFIC REPORTS, 2021, 11 (01)
  • [4] CRYSTAL-STRUCTURE OF N-ACETYL-L-LEUCINE
    WASKOWSKA, A
    LUKASZEWICZ, K
    KUZMINA, LG
    STRUTSHKOV, YT
    BULLETIN DE L ACADEMIE POLONAISE DES SCIENCES-SERIE DES SCIENCES CHIMIQUES, 1975, 23 (02): : 149 - 153
  • [5] N-Acetyl-l-leucine improves functional recovery and attenuates cortical cell death and neuroinflammation after traumatic brain injury in mice
    Nivedita Hegdekar
    Marta M. Lipinski
    Chinmoy Sarkar
    Scientific Reports, 11
  • [6] THEORETICAL CONFORMATIONAL-ANALYSIS OF N-ACETYL-L-LEUCINE METHYLAMIDE
    MAKSUMOV, IS
    ARKHIPOVA, SF
    LIPKIND, GM
    POPOV, EM
    KHIMIYA PRIRODNYKH SOEDINENII, 1975, (02): : 211 - 219
  • [7] The Effects of N-Acetyl-L-Leucine on the Improvement of Symptoms in a Patient with Multiple Sulfatase Deficiency
    Maryam Saberi-Karimian
    Mahsa Houra
    Tannaz Jamialahmadi
    Pooria Sarvghadi
    Mahlagha Nikbaf
    Saeed Akhlaghi
    Amirhosein Sahebkar
    The Cerebellum, 2023, 22 : 1250 - 1256
  • [8] Trial of N-Acetyl-L-Leucine in Niemann-Pick Disease Type C
    Bremova-Ertl, Tatiana
    Ramaswami, Uma
    Brands, Marion
    Foltan, Tomas
    Gautschi, Matthias
    Gissen, Paul
    Gowing, Francesca
    Hahn, Andreas
    Jones, Simon
    Kay, Richard
    Kolnikova, Miriam
    Arash-Kaps, Laila
    Marquardt, Thorsten
    Mengel, Eugen
    Park, Julien H.
    Reichmannova, Stella
    Schneider, Susanne A.
    Sivananthan, Siyamini
    Walterfang, Mark
    Wibawa, Pierre
    Strupp, Michael
    Martakis, Kyriakos
    NEW ENGLAND JOURNAL OF MEDICINE, 2024, 390 (05) : 421 - 431
  • [9] Hydrophobic N-acetyl-l-leucine grafted polyethylenimine as an efficient carrier for DNAzyme delivery
    Xing, Zhen
    Gao, Sai
    Han, Haobo
    Zhang, Jianxu
    Chen, Xuesi
    Yang, Yan
    Li, Quanshun
    JOURNAL OF CONTROLLED RELEASE, 2015, 213 : E146 - E147
  • [10] The Effects of N-Acetyl-L-Leucine on the Improvement of Symptoms in a Patient with Multiple Sulfatase Deficiency
    Saberi-Karimian, Maryam
    Houra, Mahsa
    Jamialahmadi, Tannaz
    Sarvghadi, Pooria
    Nikbaf, Mahlagha
    Akhlaghi, Saeed
    Sahebkar, Amirhosein
    CEREBELLUM, 2023, 22 (06) : 1250 - 1256
12345