Future directions for using estrogen receptor agonists in the treatment of acute and chronic spinal cord injury

被引:0
|
作者
Swapan K.Ray [1 ]
Supriti Samntaray [2 ]
Naren L.Banik [3 ,4 ]
机构
[1] Department of Pathology,Microbiology,and Immunology,University of South Carolina School of Medicine
[2] Department of Neurosciences,Medical University of South Carolina
[3] Department of Neurology and Neurosurgery,Medical University of South Carolina
[4] Ralph H. Johnson Veterans Administration Medical Center
关键词
Future directions for using estrogen receptor agonists in the treatment of acute and chronic spinal cord injury; SCI;
D O I
暂无
中图分类号
R651.2 [脊髓];
学科分类号
1002 ; 100210 ;
摘要
All synthetic and natural estrogen receptor agonists,including the most potent physiological molecule estrogen or estradiol(E2),work typically via activation of nuclear estrogen receptor alpha(ERα)and estrogen receptor beta(ERβ).Both ERαand ERβmodulate the expression of a variety of genes in the cells.Neurons and glial cells express ERαand ERβ.Many studies so far from our and other laboratories
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页码:1418 / 1419
页数:2
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