电针配合药物治疗帕金森病的临床研究

被引:23
作者
李昆珊 [1 ,2 ]
徐世芬 [3 ]
李璟 [1 ]
程玲 [4 ]
李国娜 [1 ]
戴明 [5 ]
王照钦 [1 ,2 ]
马晓芃 [1 ,2 ]
刘慧荣 [1 ,2 ]
马喆 [1 ,2 ]
吴焕淦 [1 ,2 ]
机构
[1] 上海中医药大学附属岳阳中西医结合医院
[2] 上海市针灸经络研究所
[3] 上海中医药大学附属市中医医院
[4] 同济大学附属东方医院
[5] 上海中医药大学附属龙华医院
关键词
针刺疗法; 电针; 帕金森病; 针药并用; 统一帕金森病评分量表; 帕金森病生活质量调查;
D O I
10.13460/j.issn.1005-0957.2020.13.1038
中图分类号
R742.5 [震颤麻痹综合征];
学科分类号
1002 ;
摘要
目的观察电针配合药物治疗帕金森病的临床疗效。方法将60例帕金森病患者随机分为治疗组和对照组,每组30例。对照组采用常规药物治疗,治疗组在对照组基础上采用电针治疗。治疗12周后,观察两组治疗前后统一帕金森病评分量表(UPDRS)评分、帕金森病生活质量调查(PDQ-39)量表评分及步行20 m所需时间和平均步距的变化情况。结果治疗组治疗8、12周后UPDRS评分逐渐下降,步行20 m所需时间逐渐缩短,与同组治疗前比较差异均具有统计学意义(P<0.05)。对照组治疗4、8、12周后UPDRS评分逐渐升高,与同组治疗前比较差异均具有统计学意义(P<0.05)。治疗组治疗12周后步行20 m平均步距增加,与同组治疗前比较差异具有统计学意义(P<0.05)。对照组治疗12周后步行20 m所需时间明显增加,平均步距明显缩短,与同组治疗前比较差异均具有统计学意义(P<0.05)。两组治疗8、12周后UPDRS评分、步行20 m所需时间及PDQ-39量表评分比较差异均具有统计学意义(P<0.05)。结论电针配合药物是一种治疗帕金森病的有效方法,能改善患者运动症状及生活质量。
引用
收藏
页码:1564 / 1569
页数:6
相关论文
共 23 条
[1]  
Effect and Potential Mechanism of Electroacupuncture Add-On Treatment in Patients with Parkinson’s Disease[J] . Fang Wang,Li Sun,Xiao-zhe Zhang,Jun Jia,Zhuo Liu,Xi-yan Huang,Shu-yang Yu,Li-jun Zuo,Chen-jie Cao,Xiao-min Wang,Wei Zhang,Andreas Sandner-Kiesling. &nbspEvidence-Based Complementary and Alternative Medi . 2015
[2]  
Effect of electroacupuncture on urinary leakage among women with stress urinary incontinence:A randomized clinical trial. Liu Z S,Liu Y,Xu H F,et al. The Journal of the American Medical Association . 2017
[3]  
TheLong-termEffectof AcupunctureforMigraineProphylaxis:ARandomized ClinicalTrial. ZhaoL,ChenJ,LiY,etal. JAMAInternMed . 2017
[4]  
Determining minimally important differences for the PDQ-39 Parkinson’s disease questionnaire. Peto V,Jenkinson C,Fitzpatrick R. Age and Ageing . 2001
[5]  
A Pilot Clinical Trial to Objectively Assess the Efficacy of Electroacupuncture on Gait in Patients with Parkinson’’s Disease Using Body Worn Sensors. Lei H,Toosizadeh N,Schwenk M et al. Plos One . 2016
[6]  
A Prospective Open-Label Study of Combined Treatment for Idiopathic Parkinson’’s Disease Using Acupuncture and Bee Venom Acupuncture as an Adjunctive Treatment. Doo K H,Lee J H,Cho S Y, et al. Journal of Alternative and Complementary Medicine . 2015
[7]  
Treatment results: Parkinson’s disease. Pollak Pierre,Fraix Valérie,Krack Paul,Moro Elena,Mendes Alexandre,Chabardes Stephan,Koudsie Adnan,Benabid Alim-Louis. Movement disorders : official journal of the Movement Disorder Society . 2002
[8]  
Acupuncture therapy for the symptoms of Parkinson’s disease. Shulman Lisa M,Wen X,Weiner William J,Bateman Dinorah,Minagar Alireza,Duncan Robert,Konefal Janet. Movement disorders : official journal of the Movement Disorder Society . 2002
[9]  
Alzheimer’’s disease and Parkinson’’s disease. Nussbaum R L,Ellis C E. The New England Journal of Medicine . 2003
[10]  
Immediate effects of acupuncture on tongue pressure including swallowing reflex latency in Parkinson’’s disease. Fukuda S,Kuriyama N,Tsuru H,etal. Acupuncture in Medicine . 2016