Optimising gene therapy of hypoparathyroidism with hematopoietic stem cells

被引：0
作者：
ZHOU Yi
机构：
来源：
中华医学杂志(英文版) | 2005年 / 03期
关键词：
parathyroid hormone · gene therapy · retroviral vectors · hematopoietic stem cells · transfection;
D O I：
暂无
中图分类号：
R582.2 [];
学科分类号：
1002 ; 100201 ;
摘要：
Background The treatment of hypoparathyroidism (HPT) is still a difficult clinical problem, which necessitates a new therapy. Gene therapy of HPT has been valuable, but how to improve the gene transfer efficiency and expression stability is a problem. This study was designed to optimize the gene therapy of HPT with hematopoietic stem cells (HSCs) recombined with the parathyroid hormone (PTH) gene.
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页码：29 / 34
页数：6
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