Feasibility of a finger prick-based self-testing kit in first- and second-degree relatives of children with coeliac disease

被引：0

作者：

Judith Pichler ^{[1
]}

Matthias Zilbauer ^{[2
]}

Franco Torrente ^{[2
]}

Robert Heuschkel ^{[2
]}

Alan Phillips ^{[3
]}

Camilla Salvestrini ^{[2
]}

机构：

[1] Department of Paediatrics and Adolescent Medicine,Medical University of Vienna,1090 Vienna,Austria

[2] Department of Paediatric Gastroenterology,Addenbrooke's Hospital,Cambridge CB2 0QQ,United Kingdom

[3] Centre for Paediatric Gastroenterology,Royal Free Hospital,London NW3 2QG,United Kingdom

来源：

World Journal of Gastroenterology | 2011年 / 17卷 / 14期

关键词：

Coeliac disease; Self-testing kit; Second-degree relatives;

D O I：

暂无

中图分类号：

R54 [心脏、血管（循环系）疾病];

学科分类号：

1002 ; 100201 ;

摘要：

AIM:To assess feasibility of a finger prick-based kit as method for self-testing of first and second-degree relatives of coeliac disease (CD) patients. METHODS:A total number of 379 subjects were invited to participate in this study,consisting of 197 first- degree and 182 second-degree relatives of CD patients. The self-testing kit (BiocardTM) was sent out with included instructions for use. Completed tests were sent back to the study coordinator for assessment. RESULTS:One hundred and ninety-six invited relatives carried out the BiocardTM test at home. Amongst these,70% were children. In 97% of the cases the test was performed correctly. Three tests revealed a positive result,all of which were later confirmed by serology and histology as coeliac disease.CONCLUSION:Our study indicates that BiocardTM test is a reliable,easy to use and well-accepted tool for home testing of first- and second-degree relatives of CD patients.

引用

页码：1840 / 1843

页数：4

共 3 条

[1]

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[2] Association of celiac disease and intestinal lymphomas and other cancers [J].

Catassi, C ;

Bearzi, I ;

Holmes, GKT .

GASTROENTEROLOGY, 2005, 128 (04) :S79-S86

[3]

Undiagnosed coeliac disease at age seven: population based prospective birth cohort study[J] . Polly J Bingley,Alistair J K Williams,Alastair J Norcross,D Joe Unsworth,Robert J Lock,Andrew R Ness,Richard W Jones.BMJ: British Medical Journal . 2004 (7435)

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