HSP70 cleavage-induced photoreceptor cell death caused by N-methyl-N-nitrosourea

被引：0

作者：

Yoshiki Koriyama

Ayako Furukawa

机构：

[1] GraduateSchoolandFacultyofPharmaceuticalSciences,SuzukaUniversityofMedicalScience

来源：

Neural Regeneration Research | 2016年 / 11卷 / 11期

关键词：

HSP70 cleavage-induced photoreceptor cell death caused by N-methyl-N-nitrosourea; cell; MNU;

D O I：

暂无

中图分类号：

R774.1 [视网膜疾病];

学科分类号：

100212 ;

摘要：

<正>Retinal degenerative diseases(RDs)such as retinitis pigmentosa(RP)are characterized by slowly progressive photoreceptor cell death,but the molecular mechanism underlying RP remains unclear.Animal models for RP have led to a better understanding of the disease pathological mechanisms,yet it remains difficult to identify an appropriate genetic model for RDs in general

引用

页码：1758 / 1759

页数：2

共 11 条

[1]

Contribution of calpains to photoreceptor cell death in N -methyl- N -nitrosourea-treated rats[J] . Takayuki Oka,Takeshi Nakajima,Yoshiyuki Tamada,Thomas R. Shearer,Mitsuyoshi Azuma. &nbspExperimental Neurology . 2006 (1)

[2]

Hsp70.1 and related lysosomal factors for necrotic neuronal death[J] . TetsumoriYamashima. &nbspJournal of Neurochemistry . 2012 (4)

[3]

Analysis of protein carbonyls with 2,4-dinitrophenyl hydrazine and its antibodies by immunoblot in two-dimensional gel electrophoresis. Nakamura A,Goto S. Journal of Biochemistry . 1996

[4]

Animal models for retinitis pigmentosa induced by MNU; disease progression, mechanisms and therapeutic trials. A. Tsubura,K. Yoshizawa,M. Kuwata. Histology and Histopathology . 2010

[5] Heat Shock Protein 70 (HSP70) Is Critical for the Photoreceptor Stress Response after Retinal Detachment via Modulating Anti-Apoptotic Akt Kinase [J].

Kayama, Maki ;

Nakazawa, Toru ;

Thanos, Aristomenis ;

Morizane, Yuki ;

Murakami, Yusuke ;

Theodoropoulou, Sofia ;

Abe, Toshiaki ;

Vavvas, Demetrios ;

Miller, Joan W. .

AMERICAN JOURNAL OF PATHOLOGY, 2011, 178 (03) :1080-1091

[6] Heat shock protein 70 induction by valproic acid delays photoreceptor cell death by N-methyl-N-nitrosourea in mice [J].

Koriyama, Yoshiki ;

Sugitani, Kayo ;

Ogai, Kazuhiro ;

Kato, Satoru .

JOURNAL OF NEUROCHEMISTRY, 2014, 130 (05) :707-719

[7]

A role of Heat Shock Protein 70 in Photoreceptor Cell Death: Potential as a Novel Therapeutic Target in Retinal Degeneration[J] . Ayako Furukawa,Yoshiki Koriyama. &nbspCNS Neurosci Ther . 2016 (1)

[8]

Pigmentary degeneration of the retina induced by N-methyl-N-nitrosourea. An experimental study in syrian hamsters. Herrold K M. Archives of Ophthalmology . 1967

[9]

Caspase-3 Inhibitor Rescues N -Methyl- N -nitrosourea-induced Retinal Degeneration in Sprague–Dawley Rats[J] . Katsuhiko Yoshizawa,Jihong Yang,Hideto Senzaki,Yoshiko Uemura,Yasuhiko Kiyozuka,Nobuaki Shikata,Yuji Oishi,Hirohiko Miki,Airo Tsubura. &nbspExperimental Eye Research . 2000 (6)

[10]

Gene therapy in animal models of autosomal dominant retinitis pigmentosa. Rossmiller B,Mao H,Lewin AS. Molecular Vision . 2012

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