新疆地区维、汉、哈族骨肉瘤患者流行病学特征分析

被引：4

作者：

杨勇 ^{[1
]}

陈江涛 ^{[1
]}

楚慧慧 ^{[2
]}

王腾飞 ^{[1
]}

宋兴华 ^{[1
]}

机构：

[1] 新疆医科大学第一附属医院

[2] 新疆生产建设兵团农四师医院

来源：

实用骨科杂志 | 2018年 / 24卷 / 02期

关键词：

骨肉瘤; 流行病学; 临床特征; 新疆地区;

D O I：

10.13795/j.cnki.sgkz.2018.02.009

中图分类号：

R738.1 [骨骼肿瘤];

学科分类号：

100214 ;

摘要：

目的探讨新疆地区骨肉瘤流行病学特征,为临床工作提供一定参考。方法回顾2002年1月至2016年6月290例骨肉瘤患者临床病历资料,收集相关流行病学信息进行统计分析。结果新疆地区骨肉瘤年患病人数整体呈上升趋势;290例骨肉瘤患者中以维吾尔族居多,占56.6%,男女比例为1.2︰1.0,平均年龄为(24.95±16.59)岁,11～20岁为发病高峰;发病部位以膝关节周围最多见(69.7%),病理学分型常规型骨肉瘤居多,占87.2%;首发症状以疼痛肿胀为主,占69.3%;入院伴有运动障碍者41.7%,发生病理性骨折者7.9%。民族分组分析发现各民族间性别、年龄分布,肿瘤发生部位及病理分型比较,差异无统计学意义(P>0.05),血清碱性磷酸酶阳性率比较,差异有统计学意义(P<0.05)。结论维吾尔族及哈萨克族患者血清碱性磷酸酶对骨肉瘤的临床价值高于汉族及其他民族。

引用

页码：130 / 133

页数：4

共 24 条

[1]

Prognostic effect of pathologic fracture in localized osteosarcoma: a cohort/case controlled study at a single institute. Kim Min S,Lee Soo-Yong,Lee Tae R,Cho Wan H,Song Won S,Cho Sang H,Lee Jun A,Yoo Ji Y,Jung Sung T,Jeon Dae-Geun. Journal of Surgery . 2009

[2] A review of clinical and molecular prognostic factors in osteosarcoma [J].

Clark, Jonathan C. M. ;

Dass, Crispin R. ;

Choong, Peter F. M. .

JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY, 2008, 134 (03) :281-297

[3] A review of clinical and molecular prognostic factors in osteosarcoma [J].

Clark, Jonathan C. M. ;

Dass, Crispin R. ;

Choong, Peter F. M. .

JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY, 2008, 134 (03) :281-297

[4]

Limb salvage: An acceptable option in select patients with pathologic fracture in high grade osteosarcoma[J] . Joel L.Mayerson. &nbspJ. Surg. Oncol. . 2010 (2)

[5]

Incidence, epidemiology and treatment results of osteosarcoma in Finland – a nationwide population-based study[J] . Mika Sampo,Mika Koivikko,Mervi Taskinen,Pentti Kallio,Aarne Kivioja,Maija Tarkkanen,Tom B?hling. &nbspActa Oncologica . 2011 (8)

[6]

Chemotherapeutic adjuvant treatment for osteosarcoma: Where do we stand?[J] . Jakob K. Anninga,Hans Gelderblom,Marta Fiocco,Judith R. Kroep,Antoni H.M. Taminiau,Pancras C.W. Hogendoorn,R. Maarten Egeler. &nbspEuropean Journal of Cancer . 2011 (16)

[7] Pathologic fracture does not influence local recurrence and survival in high-grade extremity osteosarcoma with adequate surgical margins [J].

Xie, Lu ;

Guo, Wei ;

Li, Yuanbo ;

Ji, Tao ;

Sun, Xin .

JOURNAL OF SURGICAL ONCOLOGY, 2012, 106 (07) :820-825

[8]

Osteosarcoma: the COSS experience. Bielack Stefan,Jürgens Herbert,Jundt Gernot,Kevric Matthias,Kühne Thomas,Reichardt Peter,Zoubek Andreas,Werner Mathias,Winkelmann Winfried,Kotz Rainer. Cancer treatment and research . 2010

[9]

Epidemiologic study of 112 osteosarcomas in Chiang Mai University Hospital, Thailand. Settakorn Jongkolnee,Rangdaeng Samreung,Arpornchayanon Olarn,Lekawanvijit Suree,Suwannason Patcharee,Thorner Paul S. Journal of the Medical Association of Thailand = Chotmaihet thangphaet . 2007

[10]

Long-term survivals of stage IIb osteosarcoma: a 20-year experience in a single institution. Y Cho,GH Jung,SH Chung,JY Kim,Y Choi,JD Kim. Clinics in orthopedic surgery . 2011

← 1 2 3 →