A Clinical Investigation on Zhi Ling Tang for Treatment of Senile Dementia

<正> Zhi Ling Tang（ZLT 智录汤,a TCM prescription designed for replenishing essence,supplementingmarrow,invigorating qi,warming yang,removing blood stasis and phlegm,tonifying the brain,andinvigorating mental activity）was used in 32 cases of senile dementia（SD）.After treatment,the levels ofserum cholesterol（Tch）,triglyceride（TG）,and plasma lipid peroxides（LPO）were lowered;the contentof high density lipoprotein（HDL）and the activity of superoxide dismutase（SOD）in RBC significantlyelevated,the cerebral blood flow was increased;latent period of P300 and P3 waves was shortened whilethe amplitude of P3 elevated;and topographic electroencephalogram,revised Hasegawa dementiascales （HDS）scores（P<0.05～0.01）and clinical symptoms were improved.The total effective rate was81.3 %,indicating that ZLT exhibits relatively good therapeutic effects for treating senile dementia.