Effects on proliferative activity of 1L-2 gene modified K562 cells by retroviral mediated gene transfer

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作者
NGuo XSLi XDLiu YYang NMao P HTangBeijing Institute of Basic Medical Sciences Beijing [100850 ]
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gene; Effects on proliferative activity of 1L-2 gene modified K562 cells by retroviral mediated gene transfer;
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R733.7 [白血病];
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<正> In the present study, human IL-2 gene wastransferred into human erythroleukemic cell line K562 bythe retroviral vector LYCN. The effects on theproliferative activity of the IL-2-gene-modified K562 cells(K562/IL2) were studied. 18 Days after transduction,flow cytometry analysis indicated that (K562/IL2)accumulated at phase G2. By day 30, the portion ofK562/IL2 was low at G0/G1, but still high at G2. The
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页码:324 / 324
页数:1
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