K~+/Cl~- co-transporter-2 upmodulation: a multi-modal therapy to treat spinal cord injury

被引:0
作者
Shane V.Hegarty [1 ]
Joanna Stanicka [1 ]
机构
[1] AXONIS Therapeutics,Inc.,Lab Central
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中图分类号
R651.2 [脊髓];
学科分类号
1002 ; 100210 ;
摘要
Herein,the rationale and supporting evidence for the promise of developing K~+/ Cl~- co-transporter-2 (KCC2) neuromodulatory therapies for spinal cord injury (SCI) is discussed.SCI is commonly a life-changing,unforeseen neuro t rauma that has devastating consequences for the injured person,their families and society as a whole.Because less than 1% of patients have a complete recovery,the vast majority of people after SCI have significant disabilities and can be entirely dependent upon others for assistance in their activities of daily living.
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页码:1984 / 1986
页数:3
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