Beyond peripheral nerve injury:spina gliopathy and maladaptive synaptic plasticity

被引：0

作者：

Giovanni Cirillo ^{[1
]}

Michele Papa ^{[1
]}

机构：

[1] Laboratory of Neuronal Networks,Department of Mental and Physical Health and Preventive Medicine,Second University of Naples

来源：

Neural Regeneration Research | 2016年 / 11卷 / 09期

关键词：

NGF; PNI; Beyond peripheral nerve injury;

D O I：

暂无

中图分类号：

R745 [周围神经及神经节疾病];

学科分类号：

1002 ;

摘要：

Who drew the borders between central and peripheral nervous system?A complex question but a simple answer.Human anatomy and clinical neurology need to differentiate peripheral nerves from central nervous system(CNS),peripheral or central disorders,respectively.However,there are no anatomical and functional clefts between peripheral axons and central synapses.There is a direct continuity from the periphery to the center,from

引用

页码：1422 / 1423

页数：2

共 10 条

[1] Intrathecal NGF Administration Reduces Reactive Astrocytosis and Changes Neurotrophin Receptors Expression Pattern in a Rat Model of Neuropathic Pain [J].

Cirillo, Giovanni ;

Cavaliere, Carlo ;

Bianco, Maria Rosaria ;

De Simone, Antonietta ;

Colangelo, Anna Maria ;

Sellitti, Stefania ;

Alberghina, Lilia ;

Papa, Michele .

CELLULAR AND MOLECULAR NEUROBIOLOGY, 2010, 30 (01) :51-62

[2]

A New Nerve Growth Factor-Mimetic Peptide Active on Neuropathic Pain in Rats. Anna Maria Colangelo,Maria Rosaria Bianco,Luigi Vitagliano,Carlo Cavaliere,Giovanni Cirillo,Luca De Gioia,Donatella Diana,Daniele Colombo,Cristina Redaelli,Laura Zaccaro,Giancarlo Morelli,Michele Papa,Paolo Sarmientos,Lilia Alber. The Journal of Neuroscience . 2008

[3]

Astrocytes and Microglia-Mediated Immune Response in Maladaptive Plasticity is Differently Modulated by NGF in the Ventral Horn of the Spinal Cord Following Peripheral Nerve Injury. De Luca C,Savarese L,Colangelo A M,et al. Cellular and Molecular Biology . 2016

[4]

Remodelling of supraspinal neuroglial network in neuropathic pain is featured by a reactive gliosis of the nociceptive amygdala. Marcello L,Cavaliere C,Colangelo AM,Bianco MR,Cirillo G,Alberghina L,Papa M. European journal of pain (London,England) . 2013

[5]

Astrocyte-neuron interplay in maladaptive plasticity[J] . Michele Papa,Ciro De Luca,Federica Petta,Lilia Alberghina,Giovanni Cirillo. &nbspNeuroscience and Biobehavioral Reviews . 2014

[6]

Morphine paradoxically prolongs neuropathic pain in rats by amplifying spinal NLRP3inflammasomeactivation. Grace PM,Strand KA,Galer EL,Urban DJ,Wang X,Baratta MV,Fabisiak TJ,Anderson ND,Cheng K,Greene LI,Berkelhammer D,Zhang Y,Ellis AL,Yin HH,Campeau S,Rice KC,Roth BL,Maier SF,Watkins LR. Proceedings of the National Academy of Sciences of the United States of America . 2016

[7]

Purinergic Modulation of Spinal Neuroglial Maladaptive Plasticity Following Peripheral Nerve Injury. Cirillo G,Colangelo AM,Berbenni M,et al. Molecular Neurobiology . 2015

[8]

Modulation of Matrix Metalloproteinases Activity in the Ventral Horn of the Spinal Cord Re-stores Neuroglial Synaptic Homeostasis and Neurotrophic Support following Peripheral Nerve Injury. Ciril o G,Colangelo AM,De Luca C,et al. PLoS One . 2016

[9]

BB14, a Nerve Growth Factor (NGF)-like peptide shown to be effective in reducing reactive astrogliosis and restoring synaptic homeostasis in a rat model of peripheral nerve injury[J] . Giovanni Cirillo,Anna Maria Colangelo,Maria Rosaria Bianco,Carlo Cavaliere,Laura Zaccaro,Paolo Sarmientos,Lilia Alberghina,Michele Papa. &nbspBiotechnology Advances . 2011 (1)

[10]

Reactive astrocytosis-induced perturbation of synaptic homeostasis is restored by nerve growth factor[J] . Giovanni Cirillo,Maria Rosaria Bianco,Anna Maria Colangelo,Carlo Cavaliere,De Luca Daniele,Laura Zaccaro,Lilia Alberghina,Michele Papa. &nbspNeurobiology of Disease . 2010 (3)

← 1 →