Studies on repairing of hemisected thoracic spinal cord of adult rats by using a chitosan tube filled with alginate fibers

被引：2

作者：

LI Xiaoguang YANG Zhaoyang and YANG Yi Beijing Center for Neural Regeneration and Repairing Capital University of Medical Sciences Beijing China ^{[100054
]}

Department of Bioengineering Beijing University of Aeronautics and Astronautics Beijing China ^{[100083
]}

National Center of Biomedical Analysis Beijing China ^{[100850
]}

机构：

来源：

Progress in Natural Science | 2006年 / 10期

关键词：

spinal cord injury; regeneration; function recovery; chitosan; alginate; behavioral evaluation;

D O I：

暂无

中图分类号：

Q95-33 [动物学实验（实验动物学）、动物学技术];

学科分类号：

071002 ;

摘要：

<正>A chitosan tube filled with alginate fibers was implanted into the injured spinal cord of a rat for repairing the damaged tissue. Twelve months after the operation, the morphological observation demonstrated that this chitosan tube could induce regeneration of myelinated and non-myelinated axons and blood vessels. The Basso-Beattie-Bresnahan (BBB) behavioral evaluation confirmed that the implants played a key role in the long-term restoration of rats motor functions. It is a promising start in the treatment of the patients with the injury of the spinal cord.

引用

页码：1051 / 1055

页数：5