Function and interaction of maturation-promoting factor and mitogen-activated protein kinase during meiotic maturation and fertilization of oocyte

被引:0
作者
HUO Lijun FAN Hengyu CHEN Dayuan and SUN QingyuanState Key Laboratory of Reproductive Biology Institute of Zoology Chinese Academy of Sciences Beijing China [100080 ]
机构
关键词
oocyte; meiosis; fertilization; MAP kinase; MPF;
D O I
暂无
中图分类号
Q253 [细胞生长与细胞分裂];
学科分类号
071009 ; 090102 ;
摘要
Mitogen-activated protein kinase (MAP kinase) cascade and maturation-promoting factor (MPF) play very important roles during meiotic maturation and fertilization of oocyte. Interaction between MAP kinase and MPF influences meiotic maturation and fertilization of oocyte throughout the animal kingdom, including stimulation of germinal vesicle breakdown (GVBD), suppression of DNA replication, control of meiotic chromosome segregation, maintenance of metaphase II arrest, and resumption and completion of second meiosis. This review focuses on the function and interaction of MAP kinase and MPF during meiotic maturation and fertilization of oocyte.
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页码:10 / 15
页数:6
相关论文
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[1]  
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[2]  
Roles of MAP kinase signaling pathway in oocyte meiosis[J] . Hengyu Fan,Chao Tong,Dayuan Chen,Qingyuan Sun.Chinese Science Bulletin . 2002 (14)
[3]  
MAPK regulates cell cycle progression in pig oocytes and fertilized eggs[J] . Manyu Li,Hengyu Fan,Chao Tong,Dayuan Chen,Guoliang Xia,Qingyuan Sun.Chinese Science Bulletin . 2002 (10)