Imaging mass spectrometry: a molecular microscope for studying the role of lipids in Parkinson's disease

被引：0
|
作者：
Vinata Vedam-Mai [1 ]
Jacob M.Samuel [2 ]
Boone M.Prentice [2 ]
机构：
[1] Department of Neurology, University of Florida
[2] Department of Chemistry, University of Florida
来源：
Neural Regeneration Research | 2024年 / 06期
关键词：
D O I：
暂无
中图分类号：
R742.5 [震颤麻痹综合征];
学科分类号：
1002 ;
摘要：
Parkinson’s disease–A lipidopathy? The histopathological hallmark of Parkinson’s disease(PD) and dementia with Lewy bodies are inclusions enriched in α-synuclein(α-syn), known as Lewy bodies, which are not only composed of proteins, but also a core of lipid species. PD has been thus far principally thought of as a “proteinopathy” caused by the misfolding of α-syn. However,
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页码：1179 / 1180
页数：2
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