Guillain-Barrésyndrome following hepatitis E

被引：10

作者：

Jean Philippe Loly ^{[1
]}

Estelle Rikir ^{[2
]}

Maxime Seivert ^{[1
]}

Emile Legros ^{[3
]}

Pierre Defrance ^{[4
]}

Jacques Belaiche ^{[1
]}

Gustave Moonen ^{[2
]}

Jean Delwaide ^{[1
]}

机构：

[1] Department of Hepato-Gastroenterology,CHU Sart Tilman,Universitéde Liège

[2] Department of Neurology,CHU Sart Tilman,Universitéde Liège

[3] General Practitioner 4. Department of Hepato-Gastroenterology,CHPLT La Tourelle

来源：

World Journal of Gastroenterology | 2009年 / 15卷 / 13期

关键词：

Gangliosides; Guillain-Barrésyndrome; Hepatitis E; Molecular mimicry; Viral hepatitis;

D O I：

暂无

中图分类号：

R512.6 [病毒性肝炎]; R745.43 [];

学科分类号：

1002 ; 100401 ;

摘要：

Guillain-Barrésyndrome(GBS)is often triggered by a preceding bacterial or viral infection.Occasionally,it has been observed in association with acute hepatitis A,B and C,and three cases have been previously described in India in which GBS was associated with acute hepatitis E.A molecular mimicry mechanism is supposed to be involved in the pathogenesis of GBS triggered by infectious agents,although the nature of the shared epitopes has not been characterized in most instances,including that in the case of hepatotropic viruses.We report a case of GBS following acute hepatitis E in a European individual.The presence of antiganglioside GM2 antibodies in this patient suggested molecular mimicry involving ganglioside GM2 in the pathogenesis of GBS associated with hepatitis E.

引用

页码：1645 / 1647

页数：3

共 5 条

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[2]

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[3]

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[4]

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[5]

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