CRISPR-Engineered CAR T Cells for Targeting Senescence-Associated UrokinaseType Plasminogen Activator Receptor (uPAR)

被引：0

作者：

Sarko, Lauren ^{[1
]}

Givand, David ^{[1
]}

Shepley, Claire ^{[1
]}

Attar, Allen ^{[1
]}

Kutler, Benjamin ^{[1
]}

Traynor, Roshini ^{[2
]}

Upadhyaya, Anika ^{[1
]}

Mnuk, Mackenzie ^{[1
]}

Murren, Nat ^{[1
]}

Ulland, Tyler ^{[1
]}

Kotanchek, Theresa ^{[3
]}

Saha, Krishanu ^{[1
]}

机构：

[1] Univ Wisconsin Madison, Madison, WI USA

[2] NIH Clin Ctr Bethesda, Bethesda, MD USA

[3] Evolved Analyt LLC, Rancho Santa Fe, CA USA

来源：

MOLECULAR THERAPY | 2025年 / 33卷 / 04期

关键词：

D O I：

暂无

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

266

引用

页数：1

共 4 条

[1]

Amor C., 2024, Nature Aging

[2] Senolytic CAR T cells reverse senescence-associated pathologies [J].

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Feucht, Judith ;

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Zhu, Changyu ;

Alonso-Curbelo, Direna ;

Mansilla-Soto, Jorge ;

Boyer, Jacob A. ;

Li, Xiang ;

Giavridis, Theodoros ;

Kulick, Amanda ;

Houlihan, Shauna ;

Peerschke, Ellinor ;

Friedman, Scott L. ;

Ponomarev, Vladimir ;

Piersigilli, Alessandra ;

Sadelain, Michel ;

Lowe, Scott W. .

NATURE, 2020, 583 (7814) :127-+

[3]

Bussian TJ., 2018, Nature

[4] Cellular Senescence in Neurodegenerative Diseases [J].

Martinez-Cue, Carmen ;

Rueda, Noemi .

FRONTIERS IN CELLULAR NEUROSCIENCE, 2020, 14

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