Exploring the link between metabolic syndrome risk and physical fitness in children with obesity: a cross-sectional study

被引：0

作者：

Vandoni, Matteo ^{[1
]}

Gatti, Alessandro ^{[1
,2
]}

Carnevale Pellino, Vittoria ^{[1
]}

Marin, Luca ^{[1
,3
,8
,9
]}

Cavallo, Caterina ^{[1
,4
]}

Rossi, Virginia ^{[5
]}

Lascialfari, Giulia ^{[5
]}

Zuccotti, Gianvincenzo ^{[5
,6
]}

Calcaterra, Valeria ^{[5
,7
]}

机构：

[1] Univ Pavia, Dept Publ Hlth Expt Med & Forens Sci, Lab Adapted Motor Act LAMA, I-27100 Pavia, Italy

[2] Univ Pavia, Dept Publ Hlth Expt & Forens Med, Natl PhD Programme One Hlth Approaches Infect Dis, I-27100 Pavia, Italy

[3] Healthcare Inst Citta Pavia, Dept Rehabil, I-27100 Pavia, Italy

[4] LUNEX Univ Appl Sci, Dept Sport, 50 Ave Parc Sports, L-4671 Differdange, Luxembourg

[5] Vittore Buzzi Childrens Hosp, Pediat Dept, I-20154 Milan, Italy

[6] Univ Milan, Dept Biomed & Clin Sci, I-20157 Milan, Italy

[7] Univ Pavia, Dept Internal Med, Pediat & Adolescent Unit, I-27100 Pavia, Italy

[8] Univ Pavia, Dept Clin Surg Diagnost & Pediat Sci, Lab Rehabil & Orthoped Surg LAROS, I-27100 Pavia, Italy

[9] Univ Ostrava, Fac Med, Dept Physiotherapy, Ostrava 70103, Czech Republic

来源：

EUROPEAN JOURNAL OF PEDIATRICS | 2025年 / 184卷 / 08期

关键词：

Metabolic syndrome; Physical fitness; Children; Adolescents; Obesity; CARDIORESPIRATORY FITNESS; CARDIOMETABOLIC RISK; ADOLESCENTS; CHILDHOOD; HEALTH; EXERCISE; VALIDITY; INDEX;

D O I：

10.1007/s00431-025-06339-7

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

Given the growing relevance of physical fitness for cardiometabolic health in children with obesity and the rising prevalence of MetS, this study aimed to explore the relationship between physical fitness and MetS. Specifically, the goal was to assess the relationship between physical fitness and the severity of MetS, as measured by the MetS risk score, and to evaluate the importance of each dimension as a potential indicator of metabolic health in the pediatric population. We consecutively recruited a total of 62 children and adolescents (aged 7-17 years) with obesity (BMI z-score > 2SD). For all the patients, we evaluated cardiorespiratory fitness, muscular strength, and speed-agility. We computed the MetS risk score, a continuous risk score based on BMI z-score, HDL-C, systolic blood pressure, triglycerides, and fasting glucose, and MetS was defined as having a z-score > 0.75. Cardiorespiratory fitness and speed-agility were not significantly associated with MetS. Lower limb muscular strength, measured by the standing broad jump, was inversely associated with the odds of having MetS (OR: 0.47; 0.22-0.88; 95% CI), with a 1SD (24 cm) increase in SBJ corresponding to a 53% reduction in risk. Additionally, cardiorespiratory fitness was not related to any cardiometabolic outcomes (p > 0.05), whereas muscular strength showed an inverse association with the MetS risk score (beta(2) = - 0.266, p = 0.043), BMI z-score (beta(2) = - 0.443, p = 0.001), SBP (beta(2) = - 0.304, p = 0.020), and waist-to-height ratio (beta(2) = - 0.328, p = 0.012). Conclusion: We demonstrated a link between MetS and physical fitness in children with obesity, with muscular strength showing a stronger association compared to cardiorespiratory fitness and speed-agility. The findings support the role of muscle integrity in metabolic health, emphasizing the importance of educating individuals from an early age about daily PA to promote lifelong healthy habits.

引用

页数：13

共 48 条

[1] Muscular and cardiorespiratory fitness are independently associated with metabolic risk in adolescents: the HELENA study [J].