The two-phase pressure drop characteristics of R410A flow boiling inside tubes filled with metal foams were investigated experimentally. The test sections are two tubes of 13.8 mm inner diameter filled with 5 PPI/95% porosity and 10 PPI/95% porosity metal foams separately. Experimental conditions include saturation pressure of 995 kPa, mass flux from 30 to 90 kg·m-2·s-1, heat flux from 5.9 to 16.5 kW·m-2, and inlet vapor quality from 0.175 to 0.775. The experimental results are as follows. Metal foams always increase the pressure drop of flow boiling, and the pressure drop reaches 56 kPa·m-1 at vapor quality of 0.775 and mass flux of 90 kg·m-2·s-1. The pressure drop increases with the value of PPI, and the pressure drop with 10 PPI metal foams can be as much as 1.2 times that with 5 PPI metal foams under the same working condition. A pressure drop correlation for the 13.8 mm tube filled with metal foams was developed based on the experimental data, and 90% of the predicted results agree with the experimental data within a deviation of ±15%. © All Rights Reserved.