Immunotherapy-related cystitis induced by nivolumab: A case report and review of the literature

被引：0

作者：

Yuan, Yingying ^{[1
,2
]}

Lou, Lianqing ^{[3
]}

Zhu, Siheng ^{[1
,2
]}

Yan, Dong ^{[1
,2
]}

机构：

[1] Zhejiang Univ, Affiliated Hosp 1,Collaborat Innovat Ctr Diag & Tr, Natl Clin Res Ctr Infect Dis,China Singapore Belt, Natl Med Ctr Infect Dis,State Key Lab Diag & Treat, Hangzhou, Peoples R China

[2] Yuhang Inst Collaborat Innovat & Translat Res Life, Hangzhou, Peoples R China

[3] Yiwu Cent Hosp, Dept Crit Care Med, Yiwu, Zhejiang, Peoples R China

来源：

UROLOGY CASE REPORTS | 2025年 / 62卷

关键词：

Immune checkpoint inhibitors (ICIs); Nivolumab; Immune-related cystitis; Gastric cancer;

D O I：

10.1016/j.eucr.2025.103132

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Immune checkpoint inhibitors (ICIs) like nivolumab have revolutionized cancer treatment but can cause immune-related adverse events (irAEs), including rare cystitis. This case report describes a gastric cancer patient who developed urinary symptoms, such as hematuria and frequent urination, after nivolumab treatment. Despite initial antibiotics, symptoms worsened, leading to a diagnosis of immune-related cystitis. Intravenous methylprednisolone provided rapid relief and restored renal function. Early recognition and corticosteroid treatment are crucial for managing ICI-induced cystitis and preventing unnecessary antibiotics.

引用

页数：5

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