Very low-calorie ketogenic diet and liraglutide as a synergistic strategy for the treatment of obesity: A short-term, non-randomised, observational, real-world clinical evaluation

被引：0

作者：

Camajani, Elisabetta ^{[1
,2
]}

Masi, Davide ^{[3
]}

Spizzichini, Maria Letizia ^{[3
]}

Cori, Camilla ^{[3
]}

Rossetti, Rebecca ^{[3
]}

Spoltore, Maria Elena ^{[3
]}

Tuccinardi, Dario ^{[4
,5
]}

Lubrano, Carla ^{[3
]}

Gnessi, Lucio ^{[3
]}

Isidori, Andrea M. ^{[3
]}

Gianfrilli, Daniele ^{[3
]}

Moretti, Costanzo ^{[6
]}

Caprio, Massimiliano ^{[1
,2
]}

Watanabe, Mikiko ^{[3
]}

机构：

[1] IRCCS San Raffaele, Lab Cardiovasc Endocrinol, Rome, Italy

[2] San Raffaele Open Univ, Dept Promot Human Sci & Qual Life, Rome, Italy

[3] Sapienza Univ Rome, Dept Expt Med, Sect Med Pathophysiol Food Sci & Endocrinol, I-00161 Rome, Italy

[4] Univ Campus Biomed Roma, Dept Med & Surg, Res Unit Endocrinol & Diabet, Via Alvaro Portillo 21, I-00128 Rome, Italy

[5] Fdn Policlin Univ Campus Biomed, Rome, Italy

[6] Univ Roma Tor Vergata, Dept Syst Med, Rome, Italy

来源：

DIABETES OBESITY & METABOLISM | 2025年

关键词：

adverse events; anti-obesity medication; GLP-1; analogue; GLP-1 receptor agonist; hypoglycaemia; side effects; very low-carbohydrate diet; very low-energy ketogenic therapy; VLCKD; VLEKT; weight loss; ADULTS; THERAPY; INSULIN; COSTS;

D O I：

10.1111/dom.16658

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页数：6

共 22 条

[1] Very Low Energy Ketogenic Therapy (VLEKT), Not Only a Price Matter: A Comparison Study on Average Costs of VLEKT with Fresh Foods and Replacement Meals [J].

Annunziata, Giuseppe ;

Verde, Ludovica ;

Falco, Andrea ;

Savastano, Silvia ;

Colao, Annamaria ;

Muscogiuri, Giovanna ;

Barrea, Luigi .

NUTRIENTS, 2025, 17 (03)

[2]

[Anonymous], AIFA (AIdF)

[3] Safety, tolerability and sustained weight loss over 2 years with the once-daily human GLP-1 analog, liraglutide [J].

Astrup, A. ;

Carraro, R. ;

Finer, N. ;

Harper, A. ;

Kunesova, M. ;

Lean, M. E. J. ;

Niskanen, L. ;

Rasmussen, M. F. ;

Rissanen, A. ;

Rossner, S. ;

Savolainen, M. J. ;

Van Gaal, L. .

INTERNATIONAL JOURNAL OF OBESITY, 2012, 36 (06) :843-854

[4] Ketogenic nutritional therapy (KeNuT)-a multi-step dietary model with meal replacements for the management of obesity and its related metabolic disorders: a consensus statement from the working group of the Club of the Italian Society of Endocrinology (SIE)-diet therapies in endocrinology and metabolism [J].

Barrea, L. ;

Caprio, M. ;

Camajani, E. ;

Verde, L. ;

Perrini, S. ;

Cignarelli, A. ;

Prodam, F. ;

Gambineri, A. ;

Isidori, A. M. ;

Colao, A. ;

Giorgino, F. ;

Aimaretti, G. ;

Muscogiuri, G. .

JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION, 2024, 47 (3) :487-500

[5] Very-Low-Calorie Ketogenic Diets With Whey, Vegetable, or Animal Protein in Patients With Obesity: A Randomized Pilot Study [J].

Basciani, Sabrina ;

Camajani, Elisabetta ;

Contini, Savina ;

Persichetti, Agnese ;

Risi, Renata ;

Bertoldi, Loris ;

Strigari, Lidia ;

Prossomariti, Giancarlo ;

Watanabe, Mikiko ;

Mariani, Stefania ;

Lubrano, Carla ;

Genco, Alfredo ;

Spera, Giovanni ;

Gnessi, Lucio .

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2020, 105 (09) :2939-2949

[6] Whey Protein, L-Leucine and Vitamin D Supplementation for Preserving Lean Mass during a Low-Calorie Diet in Sarcopenic Obese Women [J].

Camajani, Elisabetta ;

Persichetti, Agnese ;

Watanabe, Mikiko ;

Contini, Savina ;

Vari, Michaela ;

Di Bernardo, Settimia ;

Faro, Maria ;

Lubrano, Carla ;

Gnessi, Lucio ;

Caprio, Massimiliano ;

Basciani, Sabrina .

NUTRIENTS, 2022, 14 (09)

[7] Adapting Medication for Type 2 Diabetes to a Low Carbohydrate Diet [J].

Cucuzzella, Mark ;

Riley, Karen ;

Isaacs, Diana .

FRONTIERS IN NUTRITION, 2021, 8

[8] Impact of a very low-calorie ketogenic diet on metabolic and microbiota outcomes in post-bariatric patients and bariatric-Naïve individuals: A comparative pilot study [J].

Ernesti, Ilaria ;

Massari, Maria Chiara ;

Cipriani, Fiammetta ;

Masi, Davide ;

Glaser, Krzysztof ;

Genco, Martina ;

Tuccinardi, Dario ;

Lubrano, Carla ;

Mariani, Stefania ;

Angeloni, Antonio ;

Gnessi, Lucio ;

Basciani, Sabrina ;

Watanabe, Mikiko .

DIABETES OBESITY & METABOLISM, 2025, 27 (04) :1950-1959

[9]

European Food Safety Authority (EFSA), 2017, EFSA Supporting Publications, V14, DOI [10.2903/sp.efsa.2017.e15121, 10.2903/sp.efsa.2017.e15121, DOI 10.2903/SP.EFSA.2017.E15121]

[10] Nutrition Therapy for Adults With Diabetes or Prediabetes: A Consensus Report [J].

Evert, Alison B. ;

Dennison, Michelle ;

Gardner, Christopher D. ;

Garvey, W. Timothy ;

Lau, Ka Hei Karen ;

MacLeod, Janice ;

Mitri, Joanna ;

Pereira, Raquel F. ;

Rawlings, Kelly ;

Robinson, Shamera ;

Saslow, Laura ;

Uelmen, Sacha ;

Urbanski, Patricia B. ;

Yancy, William S., Jr. .

DIABETES CARE, 2019, 42 (05) :731-754

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