Synthesis, characterization and antimicrobial activity of N-substituted 2-substituted-benzimidazole derivatives

被引：0

作者：

Chandhrasekar, S. ^{[1
]}

Rajam, Shameela ^{[1
]}

Stella, Christina Ruby ^{[1
]}

Maruthamuthu ^{[1
]}

机构：

[1] PG and Research Department of Chemistry Bishop Heber College (Autonomous), Tiruchirappalli, Tamilnadu, India

来源：

Journal of Chemical and Pharmaceutical Research | 2012年 / 4卷 / 11期

关键词：

Hydrides - Microorganisms - Chlorine compounds - Sodium compounds;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

A series of some novel benzimidazole was synthesized and evaluated for antimicrobial activity. The reaction of ophenylenediamine with dicarboxylic acid(malonic acid, succinic acid, salicylic acid, phthalic acid) yield 2-substituted-benzimidazoles.The title compounds were synthesized by treating 2-substituted-benzimidazole with benzoyl chloride and sodium hydride.Their structures were confirmed by IR, 1H-NMR and 13C-NMR Antimicrobial activity against Pseudomonas aeruginosa was studied for the synthesized compounds.

引用

页码：4937 / 4940