Bibliometric analysis of global research trends in pancreatic cancer immunotherapy

被引：0

作者：

Fu, Tong ^{[1
]}

Chen, Yuqing ^{[2
]}

Wang, Hao ^{[3
]}

He, Linlin ^{[2
]}

Zhang, Jian ^{[4
]}

Zhou, Yongping ^{[3
]}

Duan, Xuchu ^{[5
]}

Zhang, Xu ^{[6
]}

机构：

[1] Jiangnan Univ, Wuxi Peoples Hosp 2, Affiliated Hosp, Dept Hepatobiliary Surg, Wuxi, Peoples R China

[2] Nantong Univ, Affiliated Hosp, Dept Pharm, Nantong, Peoples R China

[3] Jiangnan Univ, Nanjing Med Univ, Affiliated Wuxi Peoples Hosp 2, Wuxi Peoples Hosp 2,Dept Hepatobiliary Surg, Wuxi, Peoples R China

[4] Ordos City 2 Middle Sch, Math Res Grp, Ordos, Peoples R China

[5] Nantong Univ, Coinnovat Ctr Neuroregenerat, Sch Life Sci, Nantong Lab Dev & Dis, Nantong, Peoples R China

[6] Nanjing Med Univ, Jiangnan Univ,Clin Med Res Ctr, Nantong Univ,Affiliated Wuxi Clin Coll,Med Ctr, Wuxi Peoples Hosp 2,Affiliated Wuxi Peoples Hosp 2, Wuxi, Peoples R China

来源：

HUMAN VACCINES & IMMUNOTHERAPEUTICS | 2025年 / 21卷 / 01期

关键词：

Pancreatic cancer; immunotherapy; therapy; treatment strategies; hotspots and trends; IDENTIFY MOLECULAR SUBTYPES; EFFICACY; THERAPY; CELLS;

D O I：

10.1080/21645515.2025.2538330

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Pancreatic cancer is a highly malignant tumor with poor prognosis and limited treatments. Immunotherapy shows promise in improving outcomes, but bibliometric analyses in this field are scarce. Our work reveals emerging trends, identifies research gaps, and highlights shifts in focus, offering valuable guidance for future research of immunotherapy and clinical practice. Pancreatic cancer immunotherapy bibliometric analyses were performed utilizing tools such as CiteSpace, VOSviewer, and RStudio, with a focus on the temporal and spatial distribution, prominent authors, research themes, keywords, and citation networks. The analysis reveals a significant increase in research activity on pancreatic cancer immunotherapy over the past decade, with hotspots including ICIs, CAR-T therapy, novel biomarkers, targeted therapies, the tumor microenvironment, and personalized treatment strategies. This study systematically reviews pancreatic cancer immunotherapy research progress from 1991 to 2024, highlighting key hotspots and trends. Future efforts should focus on ICIs, CAR-T therapy, and combination strategies, to enhance outcomes and extend patient survival.

引用

页数：28

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