Management of patients with newly diagnosed multiple myeloma who are eligible for autologous stem cell transplantation: position statement of the Medical and Scientific Advisory Group of Myeloma Australia

被引：0

作者：

McCaughan, Georgia ^{[1
,2
]}

Beer, Hayley ^{[3
,4
]}

Bryant, Christian ^{[5
,6
]}

Ho, P. Joy ^{[5
,6
]}

King, Tracy ^{[5
,7
]}

Lee, Cindy ^{[8
,9
]}

Mollee, Peter ^{[10
,11
]}

Prince, H. Miles ^{[3
,4
,12
,13
,14
]}

Spencer, Andrew ^{[15
,16
]}

Talaulikar, Dipti ^{[17
,18
]}

Vandyke, Kate ^{[19
,20
]}

Weber, Nicholas ^{[21
]}

Yong, Angelina ^{[8
,9
]}

Harrison, Simon ^{[3
,22
]}

Quach, Hang ^{[12
,23
]}

机构：

[1] St Vincents Hosp, Dept Haematol, 390 Victoria Rd, Sydney, NSW 2010, Australia

[2] UNSW Med & Hlth, Sch Clin Med, Sydney, NSW, Australia

[3] Peter MacCallum Canc Ctr, Clin Haematol, Melbourne, Vic, Australia

[4] Myeloma Australia, Melbourne, Vic, Australia

[5] Royal Prince Alfred Hosp, Inst Haematol, Sydney, NSW, Australia

[6] Univ Sydney, Sydney Med Sch, Sydney, NSW, Australia

[7] Univ Sydney, Canc Nursing Res Unit, Sydney, NSW, Australia

[8] Royal Adelaide Hosp, Dept Haematol, Adelaide, SA, Australia

[9] Univ Adelaide, Adelaide Med Sch, Adelaide, SA, Australia

[10] Princess Alexandra Hosp, Dept Haematol, Brisbane, Qld, Australia

[11] Univ Queensland, Fac Med, Brisbane, Qld, Australia

[12] Univ Melbourne, Fac Med Dent & Hlth Sci, Melbourne, Vic, Australia

[13] Monash Univ, Sch Translat Med, Melbourne, Vic, Australia

[14] Epworth Healthcare, Mol Oncol & Canc Immunol, Melbourne, Vic, Australia

[15] Monash Univ, Australian Ctr Blood Dis, Melbourne, Vic, Australia

[16] Alfred Hlth, Malignant Haematol & Stem Cell Transplantat Serv, Melbourne, Vic, Australia

[17] Canberra Hlth Serv, Dept Diagnost Genom, Canberra, ACT, Australia

[18] Australian Natl Univ, Sch Med & Psychol, Canberra, ACT, Australia

[19] Univ Adelaide, Sch Biomed, Fac Hlth & Med Sci, Myeloma Res Lab, Adelaide, SA, Australia

[20] South Australian Hlth & Med Res Inst SAHMRI, Precis Med Theme, Adelaide, SA, Australia

[21] Royal Brisbane & Womens Hosp, Brisbane, Qld, Australia

[22] Univ Melbourne, Sir Peter MacCallum Dept Oncol, Melbourne, Vic, Australia

[23] St Vincents Hosp, Dept Haematol, Melbourne, Vic, Australia

来源：

INTERNAL MEDICINE JOURNAL | 2025年

关键词：

autologous stem cell transplantation; induction; maintenance; multiple myeloma; newly diagnosed; OPEN-LABEL; LENALIDOMIDE MAINTENANCE; DEXAMETHASONE INDUCTION; INTERIM ANALYSIS; BORTEZOMIB; THERAPY; CARFILZOMIB; PHASE-3; SURVIVAL; TRIAL;

D O I：

10.1111/imj.70148

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The survival of newly diagnosed patients with multiple myeloma has improved significantly over the past 20 years with significant therapeutic advances. Despite this, high-dose chemotherapy followed by autologous stem cell transplantation remains the standard of care in newly diagnosed patients who are considered transplant eligible. Here, we summarise the recommendations of the Medical and Scientific Advisory Group of Myeloma Australia for patients considered suitable for high-dose chemotherapy and autologous stem cell transplantation as part of the initial therapy.

引用

页数：11

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