Mitochondrial homeostasis orchestrates the fate of beta-cells and the outcomes of islet transplantation

被引：0

作者：

Kuang, Baicheng ^{[1
,2
]}

Zhao, Yuanyuan ^{[1
]}

Gong, Nianqiao ^{[1
]}

机构：

[1] Huazhong Univ Sci & Technol, Key Lab Organ Transplantat, Inst Organ Transplantat,Tongji Hosp,Tongji Med Col, Minist Educ,Chinese Acad Med Sci,NHC Key Lab Organ, Wuhan, Peoples R China

[2] Huazhong Univ Sci & Technol, Tongji Hosp, Tongji Med Coll, Tongji Junshan Neurosci Ctr, Wuhan, Peoples R China

来源：

CLINICAL AND TRANSLATIONAL DISCOVERY | 2025年 / 5卷 / 04期

基金：

中国国家自然科学基金;

关键词：

D O I：

10.1002/ctd2.70070

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

引用

页数：3

共 10 条

[1] β cell dedifferentiation, the underlying mechanism of diabetes in Wolfram syndrome [J].

Amo-Shiinoki, Kikuko ;

Tanabe, Katsuya ;

Nishimura, Wataru ;

Hatanaka, Masayuki ;

Kondo, Manabu ;

Kagawa, Syota ;

Zou, Meng ;

Morikawa, Shuntaro ;

Sato, Yoshihiko ;

Komatsu, Mitsuhisa ;

Mizukami, Hiroki ;

Nishida, Naoki ;

Asahara, Shun-Ichiro ;

Masutani, Hiroshi ;

Tanizawa, Yukio .

SCIENCE TRANSLATIONAL MEDICINE, 2025, 17 (786)

[2] Protective Role of Mitochondrial Uncoupling Proteins against Age-Related Oxidative Stress in Type 2 Diabetes Mellitus [J].

Cater, Masa ;

Bombek, Lidija Krizancic .

ANTIOXIDANTS, 2022, 11 (08)

[3] LRH-1/NR5A2 targets mitochondrial dynamics to reprogram type 1 diabetes macrophages and dendritic cells into an immune tolerance phenotype [J].

Cobo-Vuilleumier, Nadia ;

Rodriguez-Fernandez, Silvia ;

Lopez-Noriega, Livia ;

Lorenzo, Petra I. ;

Franco, Jaime M. ;

Lachaud, Christian C. ;

Vazquez, Eugenia Martin ;

Legido, Raquel Araujo ;

Dorronsoro, Akaitz ;

Lopez-Fernandez-Sobrino, Raul ;

Fernandez-Santos, Beatriz ;

Serrano, Carmen Espejo ;

Salas-Lloret, Daniel ;

van Overbeek, Nila ;

Ramos-Rodriguez, Mireia ;

Mateo-Rodriguez, Carmen ;

Hidalgo, Lucia ;

Marin-Canas, Sandra ;

Nano, Rita ;

Arroba, Ana I. ;

Caro, Antonio Campos ;

Vertegaal, Alfred C. O. ;

Montalvo, Alejandro Martin ;

Martin, Franz ;

Aguilar-Diosdado, Manuel ;

Piemonti, Lorenzo ;

Pasquali, Lorenzo ;

Prieto, Roman Gonzalez ;

Sanchez, Maria Isabel Garcia ;

Eizirik, Decio L. ;

Martinez-Brocca, Maria Asuncion ;

Vives-Pi, Marta ;

Gauthier, Benoit R. .

CLINICAL AND TRANSLATIONAL MEDICINE, 2024, 14 (12)

[4] LRH-1 agonist DLPC through STAT6 promotes macrophage polarization and prevents parenteral nutrition-associated cholestasis in mice [J].

Ghosh, Swati ;

Devereaux, Michael W. ;

Liu, Cuining ;

Sokol, Ronald J. .

HEPATOLOGY, 2024, 79 (05) :986-1004

[5] Harnessing cellular therapeutics for type 1 diabetes mellitus: progress, challenges, and the road ahead [J].

Grattoni, Alessandro ;

Korbutt, Gregory ;

Tomei, Alice A. ;

Garcia, Andres J. ;

Pepper, Andrew R. ;

Stabler, Cherie ;

Brehm, Michael ;

Papas, Klearchos ;

Citro, Antonio ;

Shirwan, Haval ;

Millman, Jeffrey R. ;

Melero-Martin, Juan ;

Graham, Melanie ;

Sefton, Michael ;

Ma, Minglin ;

Kenyon, Norma ;

Veiseh, Omid ;

Desai, Tejal A. ;

Nostro, M. Cristina ;

Marinac, Marjana ;

Sykes, Megan ;

Russ, Holger A. ;

Odorico, Jon ;

Tang, Qizhi ;

Ricordi, Camillo ;

Latres, Esther ;

Mamrak, Nicholas E. ;

Giraldo, Jaime ;

Poznansky, Mark C. ;

de Vos, Paul .

NATURE REVIEWS ENDOCRINOLOGY, 2025, 21 (01) :14-30

[6] Bone Marrow-Derived Mesenchymal Stem Cells Protect Islet Grafts Against Endoplasmic Reticulum Stress-Induced Apoptosis During the Early Stage After Transplantation [J].

He, Ying ;

Zhang, Dongmei ;

Zeng, Yi ;

Ma, Junlei ;

Wang, Jing ;

Guo, Hui ;

Zhang, Ji ;

Wang, Mengqin ;

Zhang, Weijie ;

Gong, Nianqiao .

STEM CELLS, 2018, 36 (07) :1045-1061

[7]

Li M, 2025, SIGNAL TRANSDUCT TAR, V10, DOI 10.1038/s41392-025-02262-3

[8] Pancreatic Islet Transplantation in Humans: Recent Progress and Future Directions [J].

Rickels, Michael R. ;

Robertson, R. Paul .

ENDOCRINE REVIEWS, 2019, 40 (02) :631-668

[9] Retrograde mitochondrial signaling governs the identity and maturity of metabolic tissues [J].

Walker, Emily M. ;

Pearson, Gemma L. ;

Lawlor, Nathan ;

Stendahl, Ava M. ;

Lietzke, Anne ;

Sidarala, Vaibhav ;

Zhu, Jie ;

Stromer, Tracy ;

Reck, Emma C. ;

Li, Jin ;

Levi-D'Ancona, Elena ;

Pasmooij, Mabelle B. ;

Hubers, Dre L. ;

Renberg, Aaron ;

Mohamed, Kawthar ;

Parekh, Vishal S. ;

Zhang, Irina X. ;

Thompson, Benjamin ;

Zhang, Deqiang ;

Ware, Sarah A. ;

Haataja, Leena ;

Qi, Nathan ;

Parker, Stephen C. J. ;

Arvan, Peter ;

Yin, Lei ;

Kaufman, Brett A. ;

Satin, Leslie S. ;

Sussel, Lori ;

Stitzel, Michael L. ;

Soleimanpour, Scott A. .

SCIENCE, 2025, 388 (6743) :167-+

[10] Mitochondria in oxidative stress, inflammation and aging: from mechanisms to therapeutic advances [J].

Xu, Xieyang ;

Pang, Yan ;

Fan, Xianqun .

SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2025, 10 (01)

← 1 →