In Beam PET Acquisition on 75 MeV. u-1 Carbon Beam Using Sampling-Based Read-Out Electronics

被引：8

作者：

Lestand, Loic ^{[1
]}

Montarou, Gerard ^{[1
]}

Force, Paul ^{[1
]}

Joly, Baptiste ^{[1
]}

Lambert, Daniel ^{[1
]}

Magne, Magali ^{[1
]}

Martin, Franck ^{[1
]}

Rozes, Arnaud ^{[1
]}

Vert, Pierre Etienne ^{[1
]}

Chadelas, Robert ^{[1
]}

机构：

[1] Laboratoire de Physique Corpusculaire, Université Blaise Pascal, CNRS, Clermont-Ferrand,F-63000, France

来源：

IEEE Transactions on Radiation and Plasma Medical Sciences | 2017年 / 1卷 / 01期

关键词：

Heavy ions - Linear accelerators - Carbon - Positron emission tomography - Medical imaging;

D O I：

10.1109/TNS.2016.2635584

中图分类号：

学科分类号：

摘要：

Positron Emission Tomography (PET) dedicated to the ion range verification in the context of hadrontherapy treatments, requires a very selective experimental device able to discriminate the two gammas from β+ decay from prompt particles due to the interactions of the beam with the matter. Prompt particles are a background noise in the context of induced β+ activity measurement. A significant part of this background noise is produced by the γ prompt emitted during beam spill. Therefore a precise knowledge of beam time structure is crucial to control the quality of data of in-beam PET acquisitions. In other words, beam time structure determines the number of primary ions per bunch and the nuclear induced background. An experiment was performed at the National Large Heavy Ion Accelerator (GANIL) in Caen (France) using a 75 A.MeV carbon beam in order to test the use of sampling-based read-out electronics to provide a very accurate time stamping of the detected particles. The experimental set-up is constituted by a small acceptance dual head detector positioned on each side of the beam centered on target. For this cyclotron beam, the cycle is 12 MHz with a beam spill of 10 ns. If acquisition takes into account only events occurring outside the spill, we demonstrate that the energy spectrum of events is equivalent to target radiative decay spectrum obtained just after stopping the beam. For this experiment, the technique of sampling signal was chosen, allowing to provide an accurate time measurement to adjust optimal time and energy cuts on the recorded data. With the time structure of the beam spill at GANIL, taking into account all the events, including those acquired during the spill, the measured background-to-signal event ratio is 10%. © 2017 IEEE.

引用

页码：87 / 95