COVID-19 patients with infective endocarditis and septic embolism to the brain

Infective endocarditis (IE), an infection of the endocardium, is an infection with serious complications such as heart failure, valvular diseases and systemic embolism. It has risk factors such as intravenous drug use, poor oral hygiene and dental intervention, and infectious symptoms such as fever, tremble, loss of appetite and weight loss. It is an infection with high morbidity and mortality that affects various organs and systems such as heart, skin and retina. Coronavirus disease (COVID-19), which can have a similar clinic with both IE and various infections, can also be seen at the same time with other infections, which causes a delay in its diagnosis and treatment. There can be similar clinical symptoms between COVID and IE during their cardiac involvement. This is another factor that creates difficulties in diagnosis. It should always be considered that COVID-19 may coexist with IE and/or other infections. Our case presented here is a patient with diabetes mellitus for 20 years and using oral antidiabetic drugs. Progressive speech disorder has occurred for two days and the patient has no history of any surgical or dental intervention, intravenous drug or drug use. IE was not considered in the initial diagnosis, and the patient was admitted to the emergency department with a prediagnosis of cerebrovascular disease and diabetes mellitus. After hospitalization in the intensive care unit, IE and septic embolism were detected with the presence of COVID-19 infection.