Benzofuran-7-yl-2,2,2-trifluoroethanols as unexpected products of the reaction of 7-trifluoroacetylbenzofurans with hydrazine hydrate

被引：0
作者：
Izgi, Samet [1 ]
Kandemir, Hakan [1 ,2 ]
Sengul, Ibrahim F. [2 ]
机构：
[1] Tekirdag Namik Kemal Univ, Fac Art & Sci, Dept Chem, Tekirdag, Turkiye
[2] Gebze Tech Univ, Fac Sci, Dept Chem, Gebze, Kocaeli, Turkiye
来源：
SYNTHETIC COMMUNICATIONS | 2025年
关键词：
Benzofuran; reduction; hydrazine hydrate; BENZOFURAN;
D O I：
10.1080/00397911.2025.2528235
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The acetylation of methoxy-activated benzofurans was successfully performed by reacting 4,6-dimethoxybenzofurans with trifluoroacetic anhydride. Unexpectedly, attempts to synthesize benzofuran-7-carbohydrazides through the reaction of 7-trifluoroacetylbenzofurans with hydrazine hydrate led to the formation of 4,6-dimethoxy-2-phenylbenzofuran-7-yl-2,2,2-trifluoroethan-1-ols. These results highlight an unexpected outcome, providing new insights into the chemistry of benzofurans.
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页数：9
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