Sensitivity enhanced surface plasmon resonance biosensor for blood cancer detection

被引：0

作者：

Ouardi, Mohamed Esseddik ^{[1
,3
]}

Meradi, Kada Abdelhafid ^{[1
,3
]}

Tayeboun, Fatima ^{[1
,2
]}

机构：

[1] Univ Ain Temouchent, Dept Sci & Technol, BP 284, Ain Temouchent 46000, Algeria

[2] Univ Djillali Liabes Sidi Bel Abbes, Sidi Bel Abbes 22000, Algeria

[3] Univ Ain Temouchent, Lab Mat Sci & Applicat LSMA, Ain Temouchent, Algeria

来源：

JOURNAL OF OPTICS-INDIA | 2025年

关键词：

Leukemia; Surface plasmon resonance; Biosensor; MATLAB; GRAPHENE;

D O I：

10.1007/s12596-025-02843-z

中图分类号：

O43 [光学];

学科分类号：

070207 ; 0803 ;

摘要：

A highly sensitive surface plasmon resonance-based (SPR) biosensor is presented in this paper. This biosensor can detect leukemia (blood cancer) and demonstrates promising performance parameters. The results of this study could be useful for health monitoring in patients at risk of blood cancer. Both leukemic and healthy blood samples were examined. The core idea of this work is to detect slight changes in the refractive index of these samples, which correspond to variations in blood composition and help determine whether a patient has blood cancer. Simulation results show remarkable values of sensitivity and figure of merit at 395 deg/RIU and 76.55 RIU(-)1, respectively. The simulations were performed using the transfer matrix method (TMM) in MATLAB.

引用

页数：8

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