A hospital-based exploration of medication adherence among outpatients with COPD: implications for clinical practice

Background: The management of COPD typically involves a multifaceted approach and a complex treatment regimen. Poor adherence to prescribed medications can lead to worsened symptoms, increased exacerbations, and reduced quality of life among patients with COPD. Objective: This study aimed to assess medication adherence and associated factors in outpatients with COPD, which remain insufficiently investigated. Methods: A cross-sectional study was conducted at outpatient respiratory clinics in two major Jordanian hospitals. Data collection included sociodemographic and medical parameters. Medication adherence was assessed using a validated Arabic 4-item scale.Logistic regression was conducted to identify the variables associated with medication adherence. Results: Of the 702 participants, 68%reported poor medication adherence. Key determinants of medication adherence included age, inhaler technique, knowledge, comorbidities, concerns about side effects, dosing frequency, disease duration, and depression. Conclusion: Medication adherence in COPD patients, particularly in the elderly, and those with comorbidities, depression, and longer disease duration, is inadequate. Effective counselling and more convenient medication regimens are essential to improving adherence in this patient population.