Quantitative electroencephalography in the diagnosis of dementia with Lewy bodies

被引：0

作者：

Mahajan, Abhimanyu ^{[1
]}

Jaramillo-Jimenez, Alberto ^{[2
]}

D'Anselmo, Anita ^{[3
]}

Prete, Giulia ^{[3
]}

Bristot, Lucrezia ^{[5
]}

Varanese, Sara ^{[4
]}

Di Domenico, Alberto ^{[3
]}

Mammarella, Nicola ^{[3
]}

Tommasi, Luca ^{[3
]}

Tinazzi, Michele ^{[5
]}

Aarsland, Dag ^{[6
]}

Babiloni, Claudio ^{[7
,8
]}

Espay, Alberto J. ^{[1
]}

Bonanni, Laura ^{[3
]}

机构：

[1] Univ Cincinnati, James J & Joan A Gardner Family Ctr Parkinsons Dis, Cincinnati, OH USA

[2] Stavanger Univ Hosp, Stavanger, Norway

[3] Univ G dAnnunzio, Via Vestini 31, Chieti, Italy

[4] Azienda Sanit Locale Lanciano Vasto Chieti, Chieti, Italy

[5] Univ Verona, Dept Neurosci Biomed & Movement Sci, Verona, Italy

[6] Kings Coll London, Dept Old Age Psychiat, Inst Psychiat Psychol & Neurosci, London, England

[7] Sapienza Univ Rome, Dept Physiol & Pharmacol V Erspamer, Rome, Italy

[8] Hosp San Raffaele Cassino, Cassino, FR, Italy

来源：

CLINICAL NEUROPHYSIOLOGY PRACTICE | 2025年 / 10卷

关键词：

quantitative EEG; Dementia; Dementia with Lewy bodies; Diagnosis; Mild cognitive impairment; RESOLUTION ELECTROMAGNETIC TOMOGRAPHY; MILD COGNITIVE IMPAIRMENT; ALZHEIMERS-DISEASE; FLUCTUATING COGNITION; PARKINSONS-DISEASE; PRODROMAL DEMENTIA; BODY DISEASES; EEG; DLB; ABNORMALITIES;

D O I：

10.1016/j.cnp.2025.06.008

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

The spectral analysis of the resting-state eyes-closed electroencephalographic (rsEEG) activity typically shows abnormal delta (< 4 Hz), theta (4-7 Hz), and alpha (8-12 Hz) power in older patients with cognitive deficits due to progressive neurodegenerative diseases. Interestingly, abnormally prominent posterior rsEEG power < 8 Hz with periodic fluctuations in the pre-alpha/theta range has been considered a supportive biomarker for diagnosing patients with prodromal or manifest dementia due to Lewy bodies (DLB) in international guidelines. Here, a panel of experts shortly reviews the concepts of thalamocortical dysrhythmia as a possible neurophysiological oscillatory mechanism generating those rsEEG abnormalities in DLB patients. It also recommends how to record and quantitatively analyze rsEEG activity in prodromal and manifesting DLB patients for the application of that cost-effective and largely available diagnostic procedure in clinical practice.

引用

页码：222 / 233

页数：12

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