Health-Related Quality of Life in Patients With a Head and Neck Sarcoma: A Mixed-Methods Study

被引：0

作者：

Koffi, E. ^{[1
,2
,3
]}

Padilla, C. S. ^{[3
,4
]}

Drabbe, C. ^{[5
]}

Schreuder, W. H. ^{[6
]}

Zemouri, C. ^{[7
]}

den Hollander, D. ^{[5
]}

Grunhagen, D. J. ^{[8
]}

Sodergren, S. ^{[9
]}

Singer, S. ^{[10
]}

Jones, R. L. ^{[11
,12
,13
]}

Desar, I. M. E. ^{[5
]}

Fauske, L. ^{[14
]}

Pinto, M. ^{[15
]}

Nixon, I. ^{[16
]}

Salah, S. ^{[17
]}

Bruland, O. S.

Soomers, V. L. M. N. ^{[5
]}

van de Sande, M. A. J. ^{[18
]}

de Haan, J. J. ^{[19
]}

Verhoef, C. ^{[8
]}

Steggink, L. C. ^{[20
]}

van Houdt, W. J. ^{[21
]}

Bootsma, T. I. ^{[3
]}

Tesselaar, M. T. ^{[22
]}

van der Graaf, W. T. A. ^{[3
,4
]}

Husson, O. ^{[3
,8
]}

机构：

[1] Vrije Univ Amsterdam, Amsterdam, Netherlands

[2] Rouen Univ, Fac Pharm, Rouen, France

[3] Netherlands Canc Inst, Dept Med Oncol, Amsterdam, Netherlands

[4] Erasmus Univ, Med Ctr, Erasmus MC Canc Inst, Dept Med Oncol, Rotterdam, Netherlands

[5] Radboud Univ Nijmegen, Dept Med Oncol, Med Ctr, Nijmegen, Netherlands

[6] Netherlands Canc Inst, Dept Head & Neck Surg & Oncol, Amsterdam, Netherlands

[7] Zemouri & Al, Publ Hlth Res, Amsterdam, Netherlands

[8] Erasmus Univ, Erasmus MC Canc Inst, Dept Surg Oncol, Dept Radiat Oncol,Med Ctr, Rotterdam, Netherlands

[9] Univ Southampton, Sch Hlth Sci, Southampton, England

[10] Univ Med Ctr Mainz, Inst Med Biostat Epidemiol & Informat, Mainz, Germany

[11] Royal Marsden Hosp, Sarcoma Unit, London, England

[12] Inst Canc Res, London, England

[13] Inst Canc Res, London, England

[14] Oslo Univ Hosp, Norwegian Radium Hosp, Dept Oncol, Oslo, Norway

[15] IRCCS Fdn G Pascale, Ist Nazl Tumori, Rehabil Med Unit, Naples, Italy

[16] Beatson Canc Ctr, Glasgow, Scotland

[17] King Fahad Specialist Hosp Dammam, Adult Med Oncol Dept, Dammam, Saudi Arabia

[18] Leiden Univ, Med Ctr, Dept Orthoped, Leiden, Netherlands

[19] Univ Med Ctr Groningen, Dept Med Oncol, Groningen, Netherlands

[20] Maastricht Univ, Med Ctr, Dept Med Oncol, Maastricht, Netherlands

[21] Netherlands Canc Inst, Dept Surg Oncol, Amsterdam, Netherlands

[22] Netherlands Canc Inst, Dept Gastrointestinal Oncol, Amsterdam, Netherlands

来源：

HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK | 2025年

关键词：

head and neck; health-related quality of life; mixed-method study; rare cancer; sarcomas; CANCER; EUROPE; NEEDS;

D O I：

10.1002/hed.28226

中图分类号：

R76 [耳鼻咽喉科学];

学科分类号：

100213 ;

摘要：

BackgroundPatients with head and neck sarcomas (HNS) face unique health-related quality of life (HRQoL) challenges due to its disease rarity. This study examined and identified the prevalence of generic- and location-specific HRQoL issues.MethodsQuantitative data from 72 HNS survivors (SURVSARC study), and qualitative data from 18 HNS patients (EORTC QoL VOICE study) were examined. Descriptive statistics was used for questionnaire data. Qualitative data was thematically analyzed.ResultsQuantitative findings showed fatigue (68%), speaking issues (50%), and dry mouth (48%) as common problems. Qualitative findings supported quantitative results and highlighted HNS-specific issues, including throat pain, impaired tongue mobility, and swelling in the face and neck.ConclusionHNS patients share symptoms with other cancers, but location-specific issues, such as lack of tongue mobility, require tailored measurement strategies. Combining generic (EORTC QLQ-C30), location-specific (EORTC QLQ-H&N43) questionnaires, and an HNS-specific item list provides a comprehensive HRQoL assessment for future research and clinical practice.

引用

页数：12

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