Pd-Catalyzed C-H Functionalization/Annulation of 2-Aryl-1,3-dicarbonyls with Vinylcyclopropanes: Merging C-H and C-C Activation

被引：0

作者：

Roy, Sajal ^{[1
]}

Saha, Sharajit ^{[1
]}

Bhattacharyya, Hemanga ^{[1
]}

Punniyamurthy, Tharmalingam ^{[1
]}

机构：

[1] Indian Inst Technol Guwahati, Dept Chem, Gauhati 781039, India

来源：

ORGANIC LETTERS | 2025年

关键词：

DERIVATIVES; ALLYLATION; ALKYNES;

D O I：

10.1021/acs.orglett.5c02216

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Pd-catalyzed enol-directed cascade C-H functionalization and annulation of 2-aryl-1,3-dicarbonyls have been developed using vinylcyclopropanes as a coupling partner. Utilization of an intrinsic weak chelating group, C-C/C-O bond formation, substrate scope, functional group tolerance, subsequent hydrogenolysis, and hydrogenation of products to furnish alkylated 2-aryl-1,3-dicarbonyls and late-stage product modifications are the important practical features.

引用

页数：5

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