A Convenient Electrochemical One-Pot Direct Synthesis of 2H-Indazoles via N-N Coupling

被引：0

作者：

Upadhyay, Abhishek ^{[1
]}

Moulekhi, Sumit ^{[1
]}

Singh, Vinay Kumar ^{[2
]}

Singh, Manjula ^{[3
]}

Patel, Manoj Kumar ^{[4
]}

Mishra, G. K. ^{[1
]}

Gupta, L. P. ^{[1
]}

Awasthi, N. K. ^{[1
]}

Singh, R. K. P. ^{[4
]}

机构：

[1] Univ Lucknow, BSNV Post Grad Coll, Dept Chem, Lucknow, India

[2] DN PG Coll, Dept Chem, Bulandshahr, India

[3] Govt Engn Coll, Dept Chem, Jamui, India

[4] Univ Allahabad, Dept Chem, Electrochem Lab Green Synth, Allahabad, India

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 2025年

关键词：

2H-Indazoles; electrosynthesis; hydrazine-and metal-free; mild reaction condition; N-N coupling; one pot synthesis; 3 COMPONENT SYNTHESIS; HETEROCYCLIC-COMPOUNDS; BOND FORMATION; INDAZOLES; ELECTROSYNTHESIS; INHIBITORS; AZIDES; MILD;

D O I：

10.1002/jhet.70018

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

This article describes an environmentally friendly synthesis of a 2H-indazole derivative via N-N bond coupling using the interaction of 2-azidobenzaldehyde and aniline in EtOH solvent. Constant Current electrosynthesis was performed in an undivided cell at ambient temperature with tetrabutylammonium hexafluorophosphate (Bu4NPF6) as a supporting electrolyte. The protocol's enticing qualities include clean synthesis, the use of electricity rather than chemical reagents, and atom economy.

引用

页数：6

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