Clinical impacts of COVID-19 on severe exacerbation and mortality in interstitial lung disease: prognosis 30 days after infection

被引：0

作者：

Kim, Bo-Guen ^{[1
]}

Lee, Sun-Kyung ^{[2
,3
]}

Park, Dong Won ^{[2
]}

Park, Tai Sun ^{[2
]}

Moon, Ji-Yong ^{[2
]}

Kim, Tae-Hyung ^{[2
]}

Kim, Sang-Heon ^{[2
]}

Yoon, Ho Joo ^{[2
]}

Lee, Hyun ^{[2
]}

机构：

[1] Sungkyunkwan Univ, Kangbuk Samsung Hosp, Dept Internal Med, Div Pulm Med,Coll Med, Seoul, South Korea

[2] Hanyang Univ, Coll Med, Dept Internal Med, Seoul, South Korea

[3] Hanyang Univ, Coll Nat Sci, Dept Math, Seoul, South Korea

来源：

KOREAN JOURNAL OF INTERNAL MEDICINE | 2025年 / 40卷 / 04期

基金：

新加坡国家研究基金会;

关键词：

COVID-19; Interstitial lung diseases; Mortality; RISK;

D O I：

10.3904/kjim.2024.388

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Results: During a mean follow-up of 7.4 months, the COVID-19 cohort had a higher risk of severe exacerbation compared to controls (aHR 2.26, 95% CI 1.38-3.69). During a mean follow-up of 19.6 months, the COVID-19 cohort had a higher risk of death (aHR 2.79, 95% CI 1.63-4.79) compared to controls. When considering COVID-19 severity, the severe COVID-19 group had a higher risk of severe exacerbation and death compared to controls, while the non-severe COVID-19 group did not show increased risk of severe exacerbation or death. In analyses based on ILD subtype, individuals with idiopathic pulmonary fibrosis in the COVID-19 cohort had the highest risk of severe exacerbation and death. Conclusions: Previous severe COVID-19 was associated with worse clinical outcomes in individuals with ILD, especially in patients with idiopathic pulmonary fibrosis.

引用

页码：634 / 644

页数：12

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