Association between life's essential 8 and colorectal cancer: A population-based study

被引：0

作者：

Ma, Xiaohan ^{[1
]}

Zhang, Xiaofei ^{[2
]}

Wu, Fasheng ^{[2
]}

Chen, Sheng ^{[1
]}

Peng, Jing ^{[1
]}

Lan, Xuan ^{[1
]}

Zhang, Xinyue ^{[1
]}

Hou, Encun ^{[2
]}

机构：

[1] Guangxi Univ Chinese Med, Grad Sch, Nanning, Guangxi, Peoples R China

[2] Guangxi Univ Chinese Med, Ruikang Hosp, Nanning 530011, Guangxi, Peoples R China

来源：

MEDICINE | 2025年 / 104卷 / 27期

关键词：

colorectal cancer; life's essential 8; risk factors; the National Health and Nutrition Examination Survey; EPIDEMIOLOGY; INEQUALITIES; HEALTH;

D O I：

10.1097/MD.0000000000043261

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Colorectal cancer (CRC) is closely linked to cardiovascular disease. This study investigates the relationship between life's essential 8 (LE8), a recent cardiovascular health metric, and CRC prevalence in US adults. Data from the 2011 to 2018 National Health and Nutrition Examination Survey were used in this study. LE8 was classified into high, moderate, and low levels. The association between LE8 and CRC was assessed using weighted logistic regression, restricted cubic splines, and subgroup analyses. After adjusting for potential confounders, higher LE8 scores were linked to a lower prevalence of CRC. Individuals with the highest LE8 scores had an 81% reduced risk of CRC compared to those with the lowest scores (odds ratio = 0.19; 95% confidence interval: 0.04-0.88, P = .03). Restricted cubic splines analyses revealed a negative correlation between CRC risk and LE8 scores, showing a linear decline as LE8 scores increased (P for non-linearity > .05). LE8 was inversely associated with CRC prevalence in a linear manner. Encouraging adherence to optimal cardiovascular health may help reduce CRC burden.

引用

页数：7

共 31 条

[11] Update of the Healthy Eating Index: HEI-2015 [J].

Krebs-Smith, Susan M. ;

Pannucci, TusaRebecca E. ;

Subar, Amy F. ;

Kirkpatrick, Sharon I. ;

Lerman, Jennifer L. ;

Tooze, Janet A. ;

Wilson, Magdalena M. ;

Reedy, Jill .

JOURNAL OF THE ACADEMY OF NUTRITION AND DIETETICS, 2018, 118 (09) :1591-1602

[12] Life's Essential 8: Updating and Enhancing the American Heart Association's Construct of Cardiovascular Health: A Presidential Advisory From the American Heart Association [J].

Lloyd-Jones, Donald M. ;

Allen, Norrina B. ;

Anderson, Cheryl A. M. ;

Black, Terrie ;

Brewer, LaPrincess C. ;

Foraker, Randi E. ;

Grandner, Michael A. ;

Lavretsky, Helen ;

Perak, Amanda Marma ;

Sharma, Garima ;

Rosamond, Wayne .

CIRCULATION, 2022, 146 (05) :E18-E43

[13] Socioeconomic inequalities in cardiovascular disease mortality - An international study [J].

Mackenbach, JP ;

Cavelaars, AEJM ;

Kunst, AE ;

Groenhof, F .

EUROPEAN HEART JOURNAL, 2000, 21 (14) :1141-1151

[14] Health Literacy and Cardiovascular Disease: Fundamental Relevance to Primary and Secondary Prevention: A Scientific Statement From the American Heart Association [J].

Magnani, Jared W. ;

Mujahid, Mahasin S. ;

Aronow, Herbert D. ;

Cene, Crystal W. ;

Dickson, Victoria Vaughan ;

Havranek, Edward ;

Morgenstern, Lewis B. ;

Paasche-Orlow, Michael K. ;

Pollak, Amy ;

Willey, Joshua Z. .

CIRCULATION, 2018, 138 (02) :E48-E74

[15] Challenging health inequalities-implications for the workplace [J].

Marmot, Michael ;

Bell, Ruth .

OCCUPATIONAL MEDICINE-OXFORD, 2010, 60 (03) :162-163

[16] Associations of Rheumatoid Arthritis and Depressive Symptoms Over Time: Are There Differences by Education, Race/Ethnicity, and Gender? [J].

McQuillan, Julia ;

Andersen, Jennifer A. ;

Berdahl, Terceira A. ;

Willett, Jeff .

ARTHRITIS CARE & RESEARCH, 2022, 74 (12) :2050-2058

[17] Heart Failure Stimulates Tumor Growth by Circulating Factors [J].

Meijers, Wouter C. ;

Maglione, Manuel ;

Bakker, Stephan J. L. ;

Oberhuber, Rupert ;

Kieneker, Lyanne M. ;

de Jong, Steven ;

Haubner, Bernhard J. ;

Nagengast, Wouter B. ;

Lyon, Alexander R. ;

van der Vegt, Bert ;

van Veldhuisen, Dirk J. ;

Westenbrink, B. Daan ;

van der Meer, Peter ;

Sillje, Herman H. W. ;

de Boer, Rudolf A. .

CIRCULATION, 2018, 138 (07) :678-691

[18] Associations Between Glycemic Traits and Colorectal Cancer: A Mendelian Randomization Analysis [J].

Murphy, Neil ;

Song, Mingyang ;

Papadimitriou, Nikos ;

Carreras-Torres, Robert ;

Langenberg, Claudia ;

Martin, Richard M. ;

Tsilidis, Konstantinos K. ;

Barroso, Ines ;

Chen, Ji ;

Frayling, Tim ;

Bull, Caroline J. ;

Vincent, Emma E. ;

Cotterchio, Michelle ;

Gruber, Stephen B. ;

Pai, Rish K. ;

Newcomb, Polly A. ;

Perez-Cornago, Aurora ;

van Duijnhoven, Franzel J. B. ;

Van Guelpen, Bethany ;

Vodicka, Pavel ;

Wolk, Alicja ;

Wu, Anna H. ;

Peters, Ulrike ;

Chan, Andrew T. ;

Gunter, Marc J. .

JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE, 2022, 114 (05) :740-752

[19] Risk Factors for Early-Onset Colorectal Cancer: A Systematic Review and Meta-analysis [J].

O'Sullivan, Dylan E. ;

Sutherland, R. Liam ;

Town, Susanna ;

Chow, Kristian ;

Fan, Jeremy ;

Forbes, Nauzer ;

Heitman, Steven J. ;

Hilsden, Robert J. ;

Brenner, Darren R. .

CLINICAL GASTROENTEROLOGY AND HEPATOLOGY, 2022, 20 (06) :1229-+

[20] Abdominal adiposity and family income-to-poverty ratio in American women [J].

Okosun, Ike S. ;

Annor, Francis B. ;

Seale, J. Paul ;

Eriksen, Michael P. .

OBESITY RESEARCH & CLINICAL PRACTICE, 2014, 8 (03) :E201-E211

← 1 2 3 4 →