Parvalbumin and Somatostatin Neurons in the Thalamic Reticular Nucleus Modulate Visual Information Processing in V1 of Mouse

被引：0

作者：

Bu, Jiamin ^{[1
]}

Xu, Guangwei ^{[1
]}

Zhou, Yifeng ^{[1
,2
]}

机构：

[1] Univ Sci & Technol China, Div Life Sci & Med, Hefei Natl Lab Phys Sci Microscale, Hefei 230026, Peoples R China

[2] Chinese Acad Sci, Inst Psychol, State Key Lab Brain & Cognit Sci, Hefei 230026, Peoples R China

来源：

NEUROSCIENCE BULLETIN | 2025年

基金：

中国国家自然科学基金;

关键词：

Thalamic reticular nucleus; Parvalbumin-positive neurons; Somatostatin-positive neurons; Primary visual cortex; Dorsal lateral geniculate nuclei; Receptive field properties; LATERAL GENICULATE-NUCLEUS; SUPERIOR COLLICULUS; RESPONSE PROPERTIES; CORTEX; GLUTAMATE; INHIBITION; CIRCUITS; CELLS; RAT; NEUROTRANSMITTER;

D O I：

10.1007/s12264-025-01458-5

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

The thalamic reticular nucleus (TRN) plays a crucial role in regulating sensory encoding, even at the earliest stages of visual processing, as evidenced by numerous studies. Orientation selectivity, a vital neural response, is essential for detecting objects through edge perception. Here, we demonstrate that somatostatin (SOM)-expressing and parvalbumin (PV)-expressing neurons in the TRN project to the dorsal lateral geniculate nucleus and modulate orientation selectivity and the capacity for visual information processing in the primary visual cortex (V1). These findings show that SOM-positive and PV-positive neurons in the TRN are powerful modulators of visual information encoding in V1, revealing a novel role for this thalamic nucleus in influencing visual processing.

引用

页数：19

共 72 条

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