Clinical characteristics and risk factors of metabolic dysfunction-associated steatotic liver disease in lean patients: results of the Polish Gallstone Surgery Registry

被引：0

作者：

Gorczyca-Glowacka, Iwona ^{[1
]}

Nawacki, Lukasz ^{[1
]}

Kolomanska, Magdalena ^{[1
]}

Mazurkiewicz, Robert ^{[1
]}

Niznik, Marcin ^{[2
]}

Ratnicki, Krzysztof ^{[2
]}

Czerniak, Malgorzata ^{[2
]}

Myrcha, Piotr ^{[3
]}

Bekarski, Maciej ^{[3
]}

Rocha-Neves, Joao ^{[4
]}

Pereira-Macedo, Juliana ^{[5
]}

Mitura, Kryspin ^{[6
]}

Kacprzak, Laura ^{[7
]}

Pajer, Malgorzata ^{[7
]}

Richter, Piotr ^{[8
]}

Rapacz, Kamil ^{[8
]}

Sroczynski, Maciej ^{[9
]}

Szmit, Mateusz ^{[9
]}

Gluszek, Stanislaw ^{[10
,11
,12
]}

机构：

[1] Jan Kochanowski Univ, Coll Med, Kielce, Poland

[2] Minist Internal & Adm, Independent Publ Hlth Care Ctr, Gdansk, Poland

[3] Med Univ Warsaw, Fac Med, Dept Gen & Vasc Surg, Warsaw, Poland

[4] Univ Porto, Fac Med, Dept Biomed, Unity Anat, Porto, Portugal

[5] Unidade Local Saude Medio Ave, Dept Surg, Vila Nova De Famalicao, Portugal

[6] Siedlce Univ Nat Sci & Humanities, Siedlce, Poland

[7] Siedlce Hosp, Siedlce, Poland

[8] Jagiellonian Univ Med Coll, Doctoral Sch Med & Hlth Sci, Dept Gen Surg 1, Krakow, Poland

[9] Wroclaw Med Univ, Dept Gen Minimally Invas & Endocrine Surg, Wroclaw, Poland

[10] Holy Cross Canc Ctr Kielce, Dept Surg Oncol, Kielce, Poland

[11] Hosp Minist Interior & Adm Kielce, Dept Surg, Kielce, Poland

[12] Polish Acad Sci, Inst Genet & Anim Biotechnol, Magdalenka, Poland

来源：

CLINICAL AND EXPERIMENTAL HEPATOLOGY | 2025年 / 11卷 / 02期

关键词：

obesity; overweight; liver steatosis; FATTY; PREVALENCE; NONOBESE; MAFLD;

D O I：

10.5114/ceh.2025.151805

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Aim of the study: Data concerning the clinical manifestation and outcomes of lean metabolic dysfunction-associated steatotic liver disease (MASLD) are scarce and inconsistent. The aim of the study was to evaluate the clinical characteristics of MASLD and predictors of its occurrence. Material and methods: The study included patients from the Polish Gallstone Surgery Registry diagnosed with MASLD according to the current criteria. Results: Among 3,419 patients, MASLD was diagnosed in 24.2%. Lean MASLD was diagnosed in 11.3% of patients with MASLD. Independent predictors of lean MASLD were atherogenic dyslipidaemia (OR = 94.16, CI: 45.54-197.71, p < 0.0001), diabetes mellitus or prediabetes conditions (OR = 9.26, CI: 4.42-19.38, p < 0.0001) and hypertension (OR = 2.97, CI: 1.38-6.41, p = 0.0054). Conclusions: Lean MASLD is not a rare form of the disease, and in the lean MASLD group there are patients with a high rate of metabolic abnormalities which may significantly increase cardiovascular risk and the risk of MASLD

引用

页码：160 / 168

页数：9

共 31 条

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