Visible-Light-Driven Synthesis of Ester-Substituted Imidazole-Fused Heterocycles via Tandem Radical Cyclization

被引：0
作者：
Yan, Qian [1 ,2 ]
Zhang, Mai [1 ,2 ]
Yao, Jie [1 ,2 ]
Zhuang, Zi-Han [1 ,2 ]
Chen, Shi-Hua [1 ,2 ]
Yang, Shi-Hai [1 ,2 ]
Li, Zhi-Wei [1 ,2 ]
Li, Jiang-Sheng [1 ,2 ]
机构：
[1] Changsha Univ Sci & Technol, Sch Chem & Pharmaceut Engn, Hunan Prov Key Lab Mat Protect Elect Power & Trans, Changsha 410114, Peoples R China
[2] Changsha Univ Sci & Technol, Sch Chem & Pharmaceut Engn, Hunan Prov Key Lab Cytochem, Changsha 410114, Peoples R China
来源：
ASIAN JOURNAL OF ORGANIC CHEMISTRY | 2025年
关键词：
Alkenes; Cascade cyclization; Nitrogen heterocycles; Photocatalysis; Radical reactions; ACCESS;
D O I：
10.1002/ajoc.202500479
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A novel tandem radical cyclization strategy is reported for the efficient synthesis of ester-functionalized imidazole-fused heterocycles. This method leverages visible-light photocatalysis and modular substrate design to achieve high regioselectivity and atom economy. The protocol demonstrates broad compatibility with diverse N-allylimidazoles and bromoacetates, enabling rapid construction of structurally complex products under mild conditions.
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页数：6
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