Progress in stability of block copolymer micelle as vehicles for drug delivery

被引：0

作者：

Liu R. ^{[1
]}

Shi Z. ^{[1
]}

Li H. ^{[2
]}

Li S. ^{[3
]}

机构：

[1] School of Medicine and Nursing, Chengdu University, Chengdu

[2] School of Bioindustry, Chengdu University, Chengdu

[3] College of Chemical Engineering, Sichuan University, Chengdu

来源：

Gaofenzi Cailiao Kexue Yu Gongcheng/Polymeric Materials Science and Engineering | 2016年 / 32卷 / 11期

关键词：

Block copolymer micelle; Crosslinking; Kinetics; Stability; Thermodynamics;

D O I：

10.16865/j.cnki.1000-7555.2016.11.033

中图分类号：

学科分类号：

摘要：

It is vital for block copolymer micelles to stabilize in blood, which favors development of sustained-release preparation with great performance. In this paper, from aspects of kinetics and thermodynamics, the factors that influence stability of the micelles were described. In succession, in terms of reducing the critical micelle concentration, enhancing the binding strength of the hydrophobic core of the micelles, and crosslinking the core or shell of micelles, different ways to enhance stability of the micelle were also reviewed. © 2016, Editorial Board of Polymer Materials Science & Engineering. All right reserved.

引用

页码：173 / 177

页数：4

共 30 条

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